Prevalence and incidence of epilepsy: a systematic review and meta-analysis of international studies
Objective: To review population-based studies of the prevalence and incidence of epilepsy
worldwide and use meta-analytic techniques to explore factors that may explain …
worldwide and use meta-analytic techniques to explore factors that may explain …
Antiseizure medications for adults with epilepsy: a review
AM Kanner, MM Bicchi - Jama, 2022 - jamanetwork.com
Importance Epilepsy affects approximately 65 million people worldwide. Persistent seizures
are associated with a 20% to 40% risk of bodily injuries (eg, fractures, burns, concussions) …
are associated with a 20% to 40% risk of bodily injuries (eg, fractures, burns, concussions) …
Comorbidities of epilepsy: current concepts and future perspectives
The burden of comorbidity in people with epilepsy is high. Several diseases, including
depression, anxiety, dementia, migraine, heart disease, peptic ulcers, and arthritis are up to …
depression, anxiety, dementia, migraine, heart disease, peptic ulcers, and arthritis are up to …
Responsive cortical stimulation for the treatment of medically intractable partial epilepsy
MJ Morrell - Neurology, 2011 - AAN Enterprises
Objectives: This multicenter, double-blind, randomized controlled trial assessed the safety
and effectiveness of responsive cortical stimulation as an adjunctive therapy for partial onset …
and effectiveness of responsive cortical stimulation as an adjunctive therapy for partial onset …
New avenues for anti-epileptic drug discovery and development
W Löscher, H Klitgaard, RE Twyman… - Nature reviews drug …, 2013 - nature.com
Despite the introduction of over 15 third-generation anti-epileptic drugs, current medications
fail to control seizures in 20–30% of patients. However, our understanding of the …
fail to control seizures in 20–30% of patients. However, our understanding of the …
A national profile of childhood epilepsy and seizure disorder
OBJECTIVE: To determine sociodemographics, patterns of comorbidity, and function of US
children with reported epilepsy/seizure disorder. METHODS: Bivariate and multivariable …
children with reported epilepsy/seizure disorder. METHODS: Bivariate and multivariable …
Management of psychiatric and neurological comorbidities in epilepsy
AM Kanner - Nature Reviews Neurology, 2016 - nature.com
The treatment of epileptic seizure disorders is not restricted to the achievement of seizure-
freedom, but must also include the management of comorbid medical, neurological …
freedom, but must also include the management of comorbid medical, neurological …
Anxiety and depressive disorders in people with epilepsy: a meta‐analysis
Objective Comorbid anxiety and depressive disorders in people with epilepsy (PWE) are
highly prevalent and associated with various adverse outcomes. However, the prevalence of …
highly prevalent and associated with various adverse outcomes. However, the prevalence of …
Epilepsy, suicidality, and psychiatric disorders: a bidirectional association
DC Hesdorffer, L Ishihara, L Mynepalli… - Annals of …, 2012 - Wiley Online Library
Objective: A study was undertaken to determine whether psychiatric disorders associated
with suicide are more common in incident epilepsy than in matched controls without …
with suicide are more common in incident epilepsy than in matched controls without …
The effects of microglia‐and astrocyte‐derived factors on neurogenesis in health and disease
Hippocampal neurogenesis continues throughout life and has been suggested to play an
essential role in maintaining spatial cognitive function under physiological conditions. An …
essential role in maintaining spatial cognitive function under physiological conditions. An …