Immunophenoty** of acute leukemia and lymphoproliferative disorders: a consensus proposal of the European LeukemiaNet Work Package 10

MC Béné, T Nebe, P Bettelheim, B Buldini, H Bumbea… - Leukemia, 2011 - nature.com
Abstract The European LeukemiaNet (ELN), workpackage 10 (WP10) was designed to deal
with diagnosis matters using morphology and immunophenoty**. This group aimed at …

Mechanisms of extramedullary relapse in acute lymphoblastic leukemia: reconciling biological concepts and clinical issues

J Gaudichon, H Jakobczyk, L Debaize, E Cousin… - Blood reviews, 2019 - Elsevier
Long-term survival rates in childhood acute lymphoblastic leukemia (ALL) are currently
above 85% due to huge improvements in treatment. However, 15-20% of children still …

EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenoty** of normal, reactive and malignant leukocytes

JJM Van Dongen, L Lhermitte, S Böttcher, J Almeida… - Leukemia, 2012 - nature.com
Most consensus leukemia & lymphoma antibody panels consist of lists of markers based on
expert opinions, but they have not been validated. Here we present the validated EuroFlow …

Commonly assessed markers in childhood BCP-ALL diagnostic panels and their association with genetic aberrations and outcome prediction

J Kulis, Ł Sędek, Ł Słota, B Perkowski, T Szczepański - Genes, 2022 - mdpi.com
Immunophenotypic characterization of leukemic cells with the use of flow cytometry (FC) is a
fundamental tool in acute lymphoblastic leukemia (ALL) diagnostics. A variety of genetic …

How do we use multicolor flow cytometry to detect minimal residual disease in acute myeloid leukemia?

J Xu, JL Jorgensen, SA Wang - Clinics in laboratory …, 2017 - labmed.theclinics.com
With the current treatment regimens, many patients with acute myeloid leukemia (AML) will
achieve a morphologic complete remission (CR) with the morphologic bone marrow (BM) …

Prognostic implications of CD9 in childhood acute lymphoblastic leukemia: insights from a nationwide multicenter study in China

KT Leung, J Cai, Y Liu, KYY Chan, J Shao, H Yang… - Leukemia, 2024 - nature.com
The outcomes of children with acute lymphoblastic leukemia (ALL) have been incrementally
improved with risk-directed chemotherapy but therapy responses remain heterogeneous …

[LIBRO][B] Flow cytometry of hematological malignancies

C Ortolani - 2021 - books.google.com
Flow Cytometry of Hematological Malignancies Flow cytometric analysis is often integral to
the swift and accurate diagnosis of leukemias and lymphomas of the blood, bone marrow …

CD9, a key actor in the dissemination of lymphoblastic leukemia, modulating CXCR4-mediated migration via RAC1 signaling

MP Arnaud, A Vallée, G Robert… - Blood, The Journal …, 2015 - ashpublications.org
CD9, a member of the tetraspanin family, has been implicated in hematopoietic and
leukemic stem cell homing. We investigated the role of CD9 in the dissemination of B acute …

CXCR4 mediates leukemic cell migration and survival in the testicular microenvironment

T Skroblyn, JJ Joedicke, M Pfau, K Krüger… - The Journal of …, 2022 - Wiley Online Library
The testis is the second most frequent extramedullary site of relapse in pediatric acute
lymphoblastic leukemia (ALL). The mechanism for B‐cell (B) ALL cell migration towards and …

Regulation of cancer stem cell properties by CD9 in human B-acute lymphoblastic leukemia

H Yamazaki, CW Xu, M Naito, H Nishida… - Biochemical and …, 2011 - Elsevier
Although the prognosis of acute lymphoblastic leukemia (ALL) has improved considerably in
recent years, some of the cases still exhibit therapy-resistant. We have previously reported …