Abstract tRNAs are key adaptor molecules that decipher the genetic code during translation
of mRNAs in protein synthesis. In contrast to the traditional view of tRNAs as ubiquitously …

RNA polymerase (Pol) III transcribes small untranslated RNAs such as 5S ribosomal RNA,
transfer RNAs, and U6 small nuclear RNA. Because of the functions of these RNAs, Pol III …

Abstract The RNA polymerase III (Pol III) transcriptome is universally comprised of short,
highly structured noncoding RNA (ncRNA). Through RNA–protein interactions, the Pol III …

Background Mammalian cells have three types of RNA polymerases (Pols), Pol I, II, and III.
However, the extent to which these polymerases are cross-regulated and the underlying …

A 1969 report that described biochemical and activity properties of the three eukaryotic RNA
polymerases revealed Pol III as highly distinguishable, even before its transcripts were …

Abstract RNA polymerase III (Pol III) synthesizes structured, essential small RNAs, such as
transfer RNA, 5S ribosomal RNA and U6 small nuclear RNA. Pol III, the largest nuclear RNA …

Summary RNA polymerase II (RNA Pol II) subunits are thought to be involved in various
transcription-associated processes, but it is unclear whether they play different regulatory …

Determination of eukaryotic transcription start sites (TSSs) has been based on methods that
require the cap structure at the 5′ end of transcripts derived from Pol II RNA polymerase …

Abstract RNA polymerase III (Pol III) transcribes essential structured small RNAs, such as
tRNAs, 5S rRNA and U6 snRNA. The transcriptional activity of Pol III is tightly controlled and …

Simple Summary Triple-negative breast cancer (TNBC) does not express estrogen or
progesterone hormone receptors and does not overexpress the HER2 transmembrane …