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Interface engineering in multiphase systems toward synthetic cells and organelles: From soft matter fundamentals to biomedical applications
Synthetic cells have a major role in gaining insight into the complex biological processes of
living cells; they also give rise to a range of emerging applications from gene delivery to …
living cells; they also give rise to a range of emerging applications from gene delivery to …
Advances in block copolymer-phospholipid hybrid vesicles: from physical-chemical properties to applications
Hybrid vesicles, made of lipids and amphiphilic block copolymers, have become
increasingly popular thanks to their versatile properties that enable the construction of …
increasingly popular thanks to their versatile properties that enable the construction of …
Constructing artificial respiratory chain in polymer compartments: Insights into the interplay between bo3 oxidase and the membrane
Cytochrome bo 3 ubiquinol oxidase is a transmembrane protein, which oxidizes ubiquinone
and reduces oxygen, while pum** protons. Apart from its combination with F1Fo-ATPase …
and reduces oxygen, while pum** protons. Apart from its combination with F1Fo-ATPase …
Biodegradable hybrid block copolymer–lipid vesicles as potential drug delivery systems
The anticipated benefits of nano-formulations for drug delivery are well known: for
nanomedicines to achieve this potential, new materials are required with predictive and …
nanomedicines to achieve this potential, new materials are required with predictive and …
Light‐driven ATP regeneration in diblock/grafted hybrid vesicles
C Kleineberg, C Wölfer, A Abbasnia, D Pischel… - …, 2020 - Wiley Online Library
Light‐driven ATP regeneration systems combining ATP synthase and bacteriorhodopsin
have been proposed as an energy supply in the field of synthetic biology. Energy is required …
have been proposed as an energy supply in the field of synthetic biology. Energy is required …
En route to dynamic life processes by SNARE-mediated fusion of polymer and hybrid membranes
A variety of artificial cells springs from the functionalization of liposomes with proteins.
However, these models suffer from low durability without repair and replenishment …
However, these models suffer from low durability without repair and replenishment …
Biomolecule–polymer hybrid compartments: combining the best of both worlds
Compartmentalization is a fundamental principle in biology that is needed for the temporal
and spatial separation of chemically incompatible reactions and biomolecules. Nano-or …
and spatial separation of chemically incompatible reactions and biomolecules. Nano-or …
PEO-b-PBD Diblock Copolymers Induce Packing Defects in Lipid/Hybrid Membranes and Improve Insertion Rates of Natively Folded Peptides
Hybrid membranes assembled from biological lipids and synthetic polymers are a promising
scaffold for the reconstitution and utilization of membrane proteins. Recent observations …
scaffold for the reconstitution and utilization of membrane proteins. Recent observations …
Hybrid vesicular drug delivery systems for cancer therapeutics
Nanoscale vesicles have provided a versatile platform for the transportation of various types
of anticancer and diagnostic agents. Vesicular carriers comprised of liposomes …
of anticancer and diagnostic agents. Vesicular carriers comprised of liposomes …
Membrane mixing and dynamics in hybrid POPC/poly (1, 2-butadiene-block-ethylene oxide)(PBd-b-PEO) lipid/block co-polymer giant vesicles
Lipids and block copolymers can individually self-assemble into vesicles, each with their
own particular benefits and limitations. Combining polymers with lipids allows for further …
own particular benefits and limitations. Combining polymers with lipids allows for further …