Progress in the diagnosis of leishmaniases depends on the development of effective
methods and the discovery of suitable biomarkers. We propose firstly an update …

Pathogenic animal trypanosomes affecting livestock have represented a major constraint to
agricultural development in Africa for centuries, and their negative economic impact is …

Trypanosoma brucei is a model trypanosomatid, an important group of human, animal and
plant unicellular parasites. Understanding their complex cell architecture and life cycle is …

Human African trypanosomiasis (HAT), or slee** sickness, is caused by Trypanosoma
brucei gambiense, which is a chronic form of the disease present in western and central …

The shape and form of protozoan parasites are inextricably linked to their pathogenicity. The
evolutionary pressure associated with establishing and maintaining an infection and …

Background Dinoflagellates are known for their capacity to form harmful blooms (eg," red
tides") and as symbiotic, photosynthetic partners for corals. These unicellular eukaryotes …

ABSTRACT TriTrypDB (http://tritrypdb. org) is an integrated database providing access to
genome-scale datasets for kinetoplastid parasites, and supporting a variety of complex …

Horizontal gene transfer (HGT; also known as lateral gene transfer) has had an important
role in eukaryotic genome evolution, but its importance is often overshadowed by the greater …

The cellular functions of the actin cytoskeleton require precise regulation of both the
initiation of actin polymerization and the organization of the resulting filaments. The actin …

Leishmania parasites cause a spectrum of clinical pathology in humans ranging from
disfiguring cutaneous lesions to fatal visceral leishmaniasis. We have generated a reference …