The nervous system governs both ontogeny and oncology. Regulating organogenesis
during development, maintaining homeostasis, and promoting plasticity throughout life, the …

The nervous system regulates tissue stem and precursor populations throughout life.
Parallel to roles in development, the nervous system is emerging as a critical regulator of …

Neural–tumor interactions drive glioma growth as evidenced in preclinical models, but
clinical validation is limited. We present an epigenetically defined neural signature of …

Cancer is a major cause of global mortality, both in affluent countries and increasingly in
develo** nations. Many patients with cancer experience reduced life expectancy and …

Glioblastoma, the most aggressive primary brain cancer, has a dismal prognosis, yet
systemic treatment is limited to DNA-alkylating chemotherapies. New therapeutic strategies …

Experience sculpts brain structure and function. Activity-dependent modulation of the
myelinated infrastructure of the nervous system has emerged as a dimension of adaptive …

Glioblastoma (GBM) is the most aggressive primary brain cancer. These tumors exhibit high
intertumoral and intratumoral heterogeneity in neoplastic and nonneoplastic compartments …

Recent advancements in understanding the tumor microenvironment (TME) have
highlighted the critical role of the nervous system in cancer progression. This review …

The mechanisms underlying the multistep process of tumorigenesis can be distilled into a
logical framework involving the acquisition of functional capabilities, the so-called hallmarks …

Despite substantial advances in cancer treatment, for patients with glioblastoma prognosis
remains bleak. The emerging field of cancer neuroscience reveals intricate functional …