[HTML][HTML] Addressing the challenges of pancreatic cancer: future directions for improving outcomes

M Hidalgo, S Cascinu, J Kleeff, R Labianca, JM Löhr… - Pancreatology, 2015 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC), which accounts for more than 90% of all
pancreatic tumours, is a devastating malignancy with an extremely poor prognosis, as …

Borderline resectable pancreatic cancer: need for standardization and methods for optimal clinical trial design

MHG Katz, R Marsh, JM Herman, Q Shi… - Annals of surgical …, 2013 - Springer
Background Methodological limitations of prior studies have prevented progress in the
treatment of patients with borderline resectable pancreatic adenocarcinoma. Shortcomings …

Efficacy of preoperative mFOLFIRINOX vs mFOLFIRINOX plus hypofractionated radiotherapy for borderline resectable adenocarcinoma of the pancreas: the A021501 …

MHG Katz, Q Shi, J Meyers, JM Herman… - JAMA …, 2022 - jamanetwork.com
Importance National guidelines endorse treatment with neoadjuvant therapy for borderline
resectable pancreatic ductal adenocarcinoma (PDAC), but the optimal strategy remains …

Response of borderline resectable pancreatic cancer to neoadjuvant therapy is not reflected by radiographic indicators

MHG Katz, JB Fleming, P Bhosale, G Varadhachary… - Cancer, 2012 - Wiley Online Library
BACKGROUND: Experience with preoperative therapy for other cancers has led to an
assumption that borderline resectable pancreatic cancers can be converted to resectable …

Laparoscopic pancreaticoduodenectomy: a systematic literature review

U Boggi, G Amorese, F Vistoli, F Caniglia, N De Lio… - Surgical …, 2015 - Springer
Background Laparoscopic pancreaticoduodenectomy (LPD) is gaining momentum, but there
is still uncertainty regarding its safety, reproducibility, and oncologic appropriateness. This …

Borderline resectable pancreatic cancer: definitions and management

NE Lopez, C Prendergast… - World journal of …, 2014 - pmc.ncbi.nlm.nih.gov
Pancreatic cancer is the fourth leading cause of cancer death in the United States. While
surgical resection remains the only curative option, more than 80% of patients present with …

Approach to patients with pancreatic cancer without detectable metastases

GM Heestand, JD Murphy, AM Lowy - Journal of clinical oncology, 2015 - ascopubs.org
The poors outcomes associated with pancreatic cancer clearly reflect the advanced stage of
disease at diagnosis for most patients. Through this lens, it is easy to lose sight of the fact …

An evaluation of the accuracy of CT when determining resectability of pancreatic head adenocarcinoma after neoadjuvant treatment

C Cassinotto, J Cortade, G Belleannée… - European journal of …, 2013 - Elsevier
BACKGROUND: To evaluate the accuracy of MDCT for determination of resectability R0
after neoadjuvant therapy in patients with pancreatic head adenocarcinoma locally …

Vascular resection for pancreatic cancer: 2019 French recommendations based on a literature review from 2008 to 6-2019

JR Delpero, A Sauvanet - Frontiers in Oncology, 2020 - frontiersin.org
Introduction: Vascular resection remains a subject of debate in the management of
Pancreatic Ductal Adenocarcinoma (PDAC). These French recommendations were drafted …

Locally advanced pancreatic adenocarcinoma: reassessment of response with CT after neoadjuvant chemotherapy and radiation therapy

C Cassinotto, A Mouries, JP Lafourcade, E Terrebonne… - Radiology, 2014 - pubs.rsna.org
Purpose To prospectively evaluate the utility of computed tomography (CT) for determination
of tumor response and prediction of resectability after neoadjuvant combined chemotherapy …