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SERS nanoparticles in medicine: from label-free detection to spectroscopic tagging
The development of diagnostic and therapeutic nanoparticles for biomedical applications is
of broad current interest in science, engineering, and medicine. The fundamental basis is …
of broad current interest in science, engineering, and medicine. The fundamental basis is …
Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy
The study of biological systems in a holistic manner (systems biology) is increasingly being
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …
Chemical Similarity Enrichment Analysis (ChemRICH) as alternative to biochemical pathway map** for metabolomic datasets
Metabolomics answers a fundamental question in biology: How does metabolism respond to
genetic, environmental or phenotypic perturbations? Combining several metabolomics …
genetic, environmental or phenotypic perturbations? Combining several metabolomics …
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
Metabolism has an essential role in biological systems. Identification and quantitation of the
compounds in the metabolome is defined as metabolic profiling, and it is applied to define …
compounds in the metabolome is defined as metabolic profiling, and it is applied to define …
[PDF][PDF] 'Omic'technologies: genomics, transcriptomics, proteomics and metabolomics.
RP Horgan, LC Kenny - Obstetrician & Gynaecologist, 2011 - researchgate.net
'Omic'technologies adopt a holistic view of the molecules that make up a cell, tissue or
organism. They are aimed primarily at the universal detection of genes (genomics), mRNA …
organism. They are aimed primarily at the universal detection of genes (genomics), mRNA …
Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry
A Hirayama, K Kami, M Sugimoto, M Sugawara… - Cancer …, 2009 - aacrjournals.org
Most cancer cells predominantly produce energy by glycolysis rather than oxidative
phosphorylation via the tricarboxylic acid (TCA) cycle, even in the presence of an adequate …
phosphorylation via the tricarboxylic acid (TCA) cycle, even in the presence of an adequate …
Plasma free amino acid profiling of five types of cancer patients and its application for early detection
Y Miyagi, M Higashiyama, A Gochi, M Akaike… - PloS one, 2011 - journals.plos.org
Background Recently, rapid advances have been made in metabolomics-based, easy-to-
use early cancer detection methods using blood samples. Among metabolites, profiling of …
use early cancer detection methods using blood samples. Among metabolites, profiling of …
Clinical applications of metabolomics in oncology: a review
JL Spratlin, NJ Serkova, SG Eckhardt - Clinical cancer research, 2009 - aacrjournals.org
Metabolomics, an omic science in systems biology, is the global quantitative assessment of
endogenous metabolites within a biological system. Either individually or grouped as a …
endogenous metabolites within a biological system. Either individually or grouped as a …
Metabolomics-based methods for early disease diagnostics
The emerging field of metabolomics, in which a large number of small-molecule metabolites
from body fluids or tissues are detected quantitatively in a single step, promises immense …
from body fluids or tissues are detected quantitatively in a single step, promises immense …
Chemometrics in metabolomics—a review in human disease diagnosis
R Madsen, T Lundstedt, J Trygg - Analytica chimica acta, 2010 - Elsevier
Metabolomics is a post genomic research field concerned with develo** methods for
analysis of low molecular weight compounds in biological systems, such as cells, organs or …
analysis of low molecular weight compounds in biological systems, such as cells, organs or …