Whole genome sequencing in clinical and public health microbiology

JC Kwong, N McCallum, V Sintchenko, BP Howden - Pathology, 2015 - Elsevier
Genomics and whole genome sequencing (WGS) have the capacity to greatly enhance
knowledge and understanding of infectious diseases and clinical microbiology. The growth …

Epidemiology and clinical management of Legionnaires' disease

N Phin, F Parry-Ford, T Harrison, HR Stagg… - The Lancet infectious …, 2014 - thelancet.com
Legionnaires' disease is an important cause of community-acquired and hospital-acquired
pneumonia. Although uncommon, Legionnaires' disease continues to cause disease …

Real-time whole-genome sequencing for routine ty**, surveillance, and outbreak detection of verotoxigenic Escherichia coli

KG Joensen, F Scheutz, O Lund… - Journal of clinical …, 2014 - journals.asm.org
Fast and accurate identification and ty** of pathogens are essential for effective
surveillance and outbreak detection. The current routine procedure is based on a variety of …

Current and emerging Legionella diagnostics for laboratory and outbreak investigations

JW Mercante, JM Winchell - Clinical microbiology reviews, 2015 - journals.asm.org
Legionnaires' disease (LD) is an often severe and potentially fatal form of bacterial
pneumonia caused by an extensive list of Legionella species. These ubiquitous freshwater …

[HTML][HTML] The bacterial pangenome as a new tool for analysing pathogenic bacteria

L Rouli, V Merhej, PE Fournier, D Raoult - New microbes and new …, 2015 - Elsevier
The bacterial pangenome was introduced in 2005 and, in recent years, has been the subject
of many studies. Thanks to progress in next-generation sequencing methods, the …

[HTML][HTML] Vancomycin-resistant Enterococcus faecium and the emergence of new sequence types associated with hospital infection

RF O'Toole, KWC Leong, V Cumming… - Research in …, 2023 - Elsevier
Enterococcus faecium is a major species in infections by vancomycin-resistant enterococci
(VRE). New variants of the pathogen have emerged and become dominant in healthcare …

Modern clinical microbiology: new challenges and solutions

PE Fournier, M Drancourt, P Colson… - Nature Reviews …, 2013 - nature.com
In the twenty-first century, the clinical microbiology laboratory plays a central part in
optimizing the management of infectious diseases and surveying local and global …

Confirmed and Potential Sources of Legionella Reviewed

E Van Heijnsbergen, JAC Schalk… - … science & technology, 2015 - ACS Publications
Legionella bacteria are ubiquitous in natural matrices and man-made systems. However, it
is not always clear if these reservoirs can act as source of infection resulting in cases of …

Recent trends in molecular diagnostics of yeast infections: from PCR to NGS

T Gabaldón - FEMS microbiology reviews, 2019 - academic.oup.com
The incidence of opportunistic yeast infections in humans has been increasing over recent
years. These infections are difficult to treat and diagnose, in part due to the large number …

Long term effect of gut microbiota transfer on diabetes development

J Peng, S Narasimhan, JR Marchesi, A Benson… - Journal of …, 2014 - Elsevier
The composition of the gut microbiome represents a very important environmental factor that
influences the development of type 1 diabetes (T1D). We have previously shown that MyD88 …