The ability of lipases to display activity beyond their physiological reactions, so-called
“catalytic promiscuity”, has gained increasing interest in the last two decades as an …

Chiral 1, 3-diols are highly valuable molecules used in industries such as pharmaceuticals,
cosmetics, and agriculture. Therefore, in this study, a new strategy was developed to …

One of the important reactions to obtain a new carbon–carbon bond is the Stetter reaction,
which is generally via a nucleophilic catalyst like cyanide or thiazolium-NHC catalysts. In …

Lipase Amano A from Aspergillus niger (AA-ANL) is among the most commonly applied
enzymes in biocatalysis processes, making it a significant scientific subject in the …

A new type of amino amide organocatalysts was designed and synthesized from
commercially available amino acids in easy steps. Their catalytic activities were examined in …

Miniemulsion systems presented a great potential for biocatalytic reactions. However,
different limitations jeopardized the applications of this non-conventional medium. In this …

The present study deals with the biocatalytic enantioselective synthesis of chiral β‐hydroxy
ketones. For the first time, we report that among many enzymes, the lipase AL‐AN (Amano …

This study provides an enzymatic kinetic resolution (EKR) method for the biocatalytic
enantioselective synthesis of chiral β‐keto acetates. For the first time, the attitude of several …

The 1, 3-hydroxycarbonyl group is an essential synthon for natural products and bioactive
organic molecules. In order to obtain this structure, a number of reaction methods have been …

Many biologically active compounds, including pharmaceuticals, are optically active and
often only one of the enantiomer shows a high biologically activity. Therefore, it is important …