The physiological function of the epidermal growth factor receptor (EGFR) is to regulate
epithelial tissue development and homeostasis. In pathological settings, mostly in lung and …

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is commonly
upregulated in cancers such as in non-small-cell lung cancer, metastatic colorectal cancer …

Glioblastoma, a rare, and highly lethal form of brain cancer, poses significant challenges in
terms of therapeutic resistance, and poor survival rates for both adult and paediatric patients …

The ERBB family of receptor tyrosine kinases has a central role in the tumorigenesis of many
types of solid tumour. Various therapeutics targeting these receptors have been approved …

The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human
epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene …

Aberrant epidermal growth factor receptor (EGFR) signaling is common in cancer. Increased
expression of wild type and mutant EGFR is a widespread feature of diverse types of cancer …

Abstract The Epidermal Growth Factor Receptor (EGFR) is frequently expressed at elevated
levels in different forms of cancer and expression often correlates positively with cancer …

Critical cellular processes are regulated, in part, by maintaining the appropriate intracellular
levels of proteins. Whereas de novo protein synthesis is a comparatively slow process …

The epidermal growth factor receptor (EGFR) is a primary contributor to glioblastoma (GBM)
initiation and progression. Here, we examine how EGFR and key downstream signaling …

Glioblastoma (glioblastoma multiforme; GBM; WHO Grade IV) accounts for the majority of
primary malignant brain tumors in adults. Amplification and mutation of the epidermal growth …