Microtubules are dynamic polymers of αβ-tubulin that are essential for intracellular
organization, organelle trafficking and chromosome segregation. Microtubule growth and …

Biological molecular motors (or biomolecular motors for short) are nature's solution to the
efficient conversion of chemical energy to mechanical movement. In biological systems …

The microtubules that comprise mitotic spindles in animal cells are nucleated at
centrosomes and by spindle assembly factors that are activated in the vicinity of chromatin …

Microtubules are born and reborn continuously, even during quiescence. These polymers
are nucleated from templates, namely γ-tubulin ring complexes (γ-TuRCs) and severed …

Microtubules are cytoskeletal polymers with two structurally and functionally distinct ends,
the plus-and the minus-end. Here, we focus on the mechanisms underlying the regulation of …

Microtubules polymerize and depolymerize stochastically, a behavior essential for cell
division, motility, and differentiation. While many studies advanced our understanding of …

Microtubules give rise to intracellular structures with diverse morphologies and dynamics
that are crucial for cell division, motility, and differentiation. They are decorated with …

How microtubules (MTs) are generated in the cell is a major question in understanding how
the cytoskeleton is assembled. For several decades, γ-tubulin has been accepted as the …

Motor-cargo recruitment to microtubules is often the rate-limiting step of intracellular
transport, and defects in this recruitment can cause neurodegenerative disease. Here, we …

Recent developments in image processing have greatly advanced our understanding of
biomolecular processes in vitro and in vivo. In particular, using Gaussian models to fit the …