Autophagy and apoptosis cascade: which is more prominent in neuronal death?

R Gupta, RK Ambasta, P Kumar - Cellular and molecular life sciences, 2021 - Springer
Autophagy and apoptosis are two crucial self-destructive processes that maintain cellular
homeostasis, which are characterized by their morphology and regulated through signal …

In vitro anti-inflammatory properties of honey flavonoids: A review

B Silva, FC Biluca, LV Gonzaga, R Fett… - Food research …, 2021 - Elsevier
Honey is a natural ready-to-eat product rich in flavonoids, which is known by the wound
healing properties due to both antibacterial and antioxidant activity. Flavonoids mitigate …

Naringin and naringenin polyphenols in neurological diseases: understandings from a therapeutic viewpoint

TB Emran, F Islam, N Nath, H Sutradhar, R Das, S Mitra… - Life, 2022 - mdpi.com
The glycosides of two flavonoids, naringin and naringenin, are found in various citrus fruits,
bergamots, tomatoes, and other fruits. These phytochemicals are associated with multiple …

Therapeutic benefits of flavonoids against neuroinflammation: a systematic review

Hamsalakshmi, AM Alex, M Arehally Marappa… - …, 2022 - Springer
Flavonoids are an important class of natural polyphenolic compounds reported to exert
beneficial effects in cardiovascular and metabolic diseases, cancer, autoimmune and …

Therapeutic potential of PPARγ natural agonists in liver diseases

L Wu, C Guo, J Wu - Journal of cellular and molecular …, 2020 - Wiley Online Library
Peroxisome proliferator‐activated receptor gamma (PPARγ) is a vital subtype of the PPAR
family. The biological functions are complex and diverse. PPARγ plays a significant role in …

Therapeutic potential of naringin in neurological disorders

S Ahmed, H Khan, M Aschner, MM Hasan… - Food and Chemical …, 2019 - Elsevier
Neurological illnesses are multifactorial incurable debilitating disorders that may cause
neurodegeneration. These diseases influence approximately 30 million people around the …

Citrus polyphenols in brain health and disease: current perspectives

MG Pontifex, MMAH Malik, E Connell… - Frontiers in …, 2021 - frontiersin.org
In addition to essential micronutrients such as vitamin C, citrus fruits represent a
considerably rich source of non-essential bioactive compounds, in particular flavanones …

Neuroprotective natural products' regulatory effects on depression via gut–brain axis targeting tryptophan

H Liaqat, A Parveen, SY Kim - Nutrients, 2022 - mdpi.com
L-tryptophan (Trp) contributes to regulating bilateral communication of the gut–brain axis. It
undergoes three major metabolic pathways, which lead to formation of kynurenine …

Role of flavonoids in neurodegenerative diseases: limitations and future perspectives

G Maan, B Sikdar, A Kumar, R Shukla… - Current Topics in …, 2020 - ingentaconnect.com
Background: Flavonoids, a group of natural dietary polyphenols, are known for their
beneficial effects on human health. By virtue of their various pharmacological effects, like …

Naringin enhances long-term potentiation and recovers learning and memory deficits of amyloid-beta induced Alzheimer's disease-like behavioral rat model

GY Choi, HB Kim, ES Hwang, HS Park, JM Cho… - Neurotoxicology, 2023 - Elsevier
Abstract Alzheimer's disease (AD), as the most typical type of dementia, is a chronic
neurodegenerative disorder characterized by progressive learning and memory impairment …