Masquelet's induced membrane technique (MIMT) is a relatively new, two‐stage surgical
procedure to reconstruct segmental bone defects. First performed by Dr. Masquelet in the …

A variety of engineered materials have gained acceptance in orthopedic practice as
substitutes for autologous bone grafts, although the regenerative efficacy of these …

Bone transport is a surgery-driven procedure for the treatment of large bone defects.
However, challenging complications include prolonged consolidation, docking site …

Bone reconstruction within a critical‐sized defect remains a real challenge in orthopedic
surgery. The Masquelet technique is an innovative, two‐step therapeutic approach for bone …

Thanks to its biological properties, the human amniotic membrane (HAM) combined with a
bone substitute could be a single-step surgical alternative to the two-step Masquelet …

Critical-size long bone defects represent one of the major causes of fracture non-union and
remain a significant challenge in orthopaedic surgery. Two-stage procedures such as a …

Autologous bone grafts are considered the gold standard grafting material for the treatment
of nonunion, but in very large bone defects, traditional autograft alone is insufficient to …

Over the last few decades, polymers and their composites have shown a lot of promises in
providing more viable alternatives to surgical procedures that require scaffolds and implants …

Critical-sized bone defects resulting from trauma, inflammation, and tumor resections are
individual in their size and shape. Implants for the treatment of such defects have to consider …

In vivo bioreactors are a promising approach for engineering vascularized autologous bone
grafts to repair large bone defects. In this pilot parametric study, we first developed a three …