Brucellae as resilient intracellular pathogens: epidemiology, host–pathogen interaction, recent genomics and proteomics approaches, and future perspectives

AS Dawood, A Elrashedy, M Nayel… - Frontiers in Veterinary …, 2023 - frontiersin.org
Brucellosis is considered one of the most hazardous zoonotic diseases all over the world. It
causes formidable economic losses in developed and develo** countries. Despite the …

[HTML][HTML] Getting to the point: unipolar growth of Hyphomicrobiales

J Amstutz, E Krol, A Verhaeghe, X De Bolle… - Current opinion in …, 2024 - Elsevier
Highlights•Unipolar growth relies on a conserved set of genes distinct from the Rod
system.•PBP1a is the primary driver of unipolar peptidoglycan biosynthesis.•Growth polarity …

[HTML][HTML] Brucella melitensis Rev1Δwzm: Placental pathogenesis studies and safety in pregnant ewes

I Poveda-Urkixo, S Mena-Bueno, GA Ramírez… - Vaccine, 2024 - Elsevier
One of the main causes of human brucellosis is Brucella melitensis infecting small
ruminants. To date, Rev1 is the only vaccine successfully used to control ovine and caprine …

A Review on the Methodology and Use of the Pregnant Mouse Model in the Study of Brucella Reproductive Pathogenesis and Its Abortifacient Effect

A Elizalde-Bielsa, PM Muñoz, A Zúñiga-Ripa… - Microorganisms, 2024 - mdpi.com
Brucellosis is one of the most common and widespread bacterial zoonoses and is caused by
Gram-negative bacteria belonging to the genus Brucella. These organisms are able to infect …

Cell and Tissue Tropism of Brucella spp.

TP Carvalho, LA Silva, TLL Castanheira… - Infection and …, 2023 - journals.asm.org
Brucella spp. are facultatively intracellular bacteria that can infect, survive, and multiply in
various host cell types in vivo and/or in vitro. The genus Brucella has markedly expanded in …

[PDF][PDF] Exploring in vivo and in vitro infection models in brucellosis research: A mini-review

T Jamil, S Iqbal, V Sandalakis - Ger. J. Vet. Res, 2024 - gmpc-akademie.de
Brucellosis is a serious disease that affects both animals and humans. It is caused by
consuming unpasteurized dairy products that are contaminated with the Brucella bacteria …

[HTML][HTML] Vaccine properties of Brucella melitensis 16MΔwzm and reactivation of placental infection in pregnant sheep

A Zabalza-Baranguá, I Poveda-Urkixo, S Mena-Bueno… - Vaccine, 2023 - Elsevier
Brucellosis, a worldwide zoonotic disease, is endemic in many develo** countries.
Besides causing significant economic losses for the livestock industry, it has severe …

BruSIC: a novel selective medium for the primary isolation of Brucella in veterinary samples

S Mena-Bueno, I Poveda-Urkixo, D Asensio… - Microbiology …, 2022 - journals.asm.org
Brucellosis, a re-emerging zoonotic infection, threatens animal welfare and public health
with serious economic consequences. A definitive diagnosis requires Brucella isolation by …

[HTML][HTML] Rev1Δwzm vaccine candidate is safe in young and adult sheep and protects against Brucella ovis infection in rams

S Mena-Bueno, V Garrido, F Romero… - Vaccine, 2024 - Elsevier
Small ruminants affected by brucellosis, caused mainly by Brucella melitensis and B. ovis,
suffer reproductive disorders, leading to significant economic losses worldwide. Vaccination …

[PDF][PDF] Biophysical characterization of Brucella abortus S19 perand evaluation of cross protective efficacy in mice model

S Anbazhagan - 2024 - krishikosh.egranth.ac.in
Brucellosis is a neglected and emerging zoonotic disease worldwide. In India, brucellosis
affects livestock, wild animals, and humans and causes a significant economic impact …