Objectives To review the evidence for an association of white matter hyperintensities with
risk of stroke, cognitive decline, dementia, and death. Design Systematic review and meta …

White matter hyperintensities (WMHs) in the brain are the consequence of cerebral small
vessel disease, and can easily be detected on MRI. Over the past three decades, research …

Cerebral small vessel disease (SVD) is a common accompaniment of ageing. Features seen
on neuroimaging include recent small subcortical infarcts, lacunes, white matter …

The pathway leading from amyloid-β deposition to cognitive impairment is believed to be a
cornerstone of the pathogenesis of Alzheimer's disease (AD). However, what drives amyloid …

Post-stroke dementia (PSD) or post-stroke cognitive impairment (PSCI) may affect up to one
third of stroke survivors. Various definitions of PSCI and PSD have been described. We …

Background and Purpose—One in 3 individuals will experience a stroke, dementia or both.
Moreover, twice as many individuals will have cognitive impairment short of dementia as …

Implementation of amyloid biomarkers in clinical practice would be accelerated if such
biomarkers could be measured in blood. We analyzed plasma levels of Aβ42 and Aβ40 in a …

Background: Several sets of diagnostic criteria have been published for vascular dementia
since the 1960s. The continuing ambiguity in vascular dementia definition warrants a critical …

Objectives We aimed to objectify and compare persisting self‐reported symptoms in initially
hospitalized and non‐hospitalized patients after infection with severe acute respiratory …

Background White matter hyperintensities of presumed vascular origin (WMH) are one of the
imaging features of cerebral small vessel disease. Controversies persist about the effects of …