Efforts are ongoing to map synaptic wiring diagrams, or connectomes, to understand the
neural basis of brain function. However, chemical synapses represent only one type of …

Animals rely on their nervous systems to process sensory inputs, integrate these with
internal signals, and produce behavioral outputs. This is enabled by the highly specialized …

The studies of cell fate and lineage specification are fundamental to our understanding of
the development of multicellular organisms. Caenorhabditis elegans has been one of the …

Axons must project to particular brain regions, contact adjacent neurons, and choose
appropriate synaptic targets to form a nervous system. Multiple mechanisms have been …

For more than a century, the origin and evolution of the arthropod head and brain have
eluded a unifying rationale reconciling divergent morphologies and phylogenetic …

Visualizing synaptic connectivity has traditionally relied on time-consuming electron
microscopy-based imaging approaches. To scale the analysis of synaptic connectivity …

Homeobox genes are prominent regulators of neuronal identity, but the extent to which their
function has been probed in animal nervous systems remains limited. In the nematode …

Map** neurotransmitter identities to neurons is key to understanding information flow in a
nervous system. It also provides valuable entry points for studying the development and …

In animals, the nervous system evolved as the primary interface between multicellular
organisms and the environment. As organisms became larger and more complex, the …

In vertebrates, thyrostimulin is a highly conserved glycoprotein hormone that, besides
thyroid stimulating hormone (TSH), is a potent ligand of the TSH receptor. Thyrostimulin is …