Roles of Porphyromonas gingivalis and its virulence factors in periodontitis

W Xu, W Zhou, H Wang, S Liang - Advances in protein chemistry and …, 2020 - Elsevier
Periodontitis is an infection-driven inflammatory disease, which is characterized by gingival
inflammation and bone loss. Periodontitis is associated with various systemic diseases …

Recent advances in engineered materials for immunotherapy‐involved combination cancer therapy

JL Liang, GF Luo, WH Chen, XZ Zhang - Advanced Materials, 2021 - Wiley Online Library
Immunotherapy that can activate immunity or enhance the immunogenicity of tumors has
emerged as one of the most effective methods for cancer therapy. Nevertheless, single …

Axial spondyloarthritis: new advances in diagnosis and management

C Ritchlin, IE Adamopoulos - Bmj, 2021 - bmj.com
Axial spondyloarthritis (axSpA) is an inflammatory disease of the axial skeleton associated
with significant pain and disability. Previously, the diagnosis of ankylosing spondylitis …

[HTML][HTML] Short chain fatty acids, a possible treatment option for autoimmune diseases

F Golpour, M Abbasi-Alaei, F Babaei… - Biomedicine & …, 2023 - Elsevier
Gut microbiota can interact with the immune system through its metabolites. Short-chain fatty
acids (SCFAs), as one of the most abundant metabolites of the resident gut microbiota play …

T helper cells: the modulators of inflammation in multiple sclerosis

M Kunkl, S Frascolla, C Amormino, E Volpe, L Tuosto - Cells, 2020 - mdpi.com
Multiple sclerosis (MS) is a chronic neurodegenerative disease characterized by the
progressive loss of axonal myelin in several areas of the central nervous system (CNS) that …

[HTML][HTML] Roles of endoplasmic reticulum stress in immune responses

JS So - Molecules and cells, 2018 - Elsevier
The endoplasmic reticulum (ER) is a critical organelle for protein synthesis, folding and
modification, and lipid synthesis and calcium storage. Dysregulation of ER functions leads to …

The cytokine IL-17A limits Th17 pathogenicity via a negative feedback loop driven by autocrine induction of IL-24

WP Chong, MJ Mattapallil, K Raychaudhuri, SJ Bing… - Immunity, 2020 - cell.com
Dysregulated Th17 cell responses underlie multiple inflammatory and autoimmune
diseases, including autoimmune uveitis and its animal model, EAU. However, clinical trials …

A role for Th1-like Th17 cells in the pathogenesis of inflammatory and autoimmune disorders

AN Kamali, SM Noorbakhsh, H Hamedifar… - Molecular …, 2019 - Elsevier
Abstract The T helper 17 (Th17) cells contain a dynamic subset of CD4+ T-cells that are able
to develop into other different lineage subsets, including the Th1-like Th17 cells. These cells …

Classical examples of the concept of the ASIA syndrome

V Borba, A Malkova, N Basantsova, G Halpert… - Biomolecules, 2020 - mdpi.com
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) was first introduced in
2011 by Shoenfeld et al. and encompasses a cluster of related immune mediated diseases …

Protective effect of epigallocatechin-3-gallate (EGCG) in diseases with uncontrolled immune activation: could such a scenario be helpful to counteract COVID-19?

M Menegazzi, R Campagnari, M Bertoldi… - International Journal of …, 2020 - mdpi.com
Some coronavirus disease 2019 (COVID-19) patients develop acute pneumonia which can
result in a cytokine storm syndrome in response to Severe Acute Respiratory Syndrome …