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Correlates of protection against SARS‐CoV‐2 infection and COVID‐19 disease
Antibodies against epitopes in S1 give the most accurate CoP against infection by the SARS‐
CoV‐2 coronavirus. Measurement of those antibodies by neutralization or binding assays …
CoV‐2 coronavirus. Measurement of those antibodies by neutralization or binding assays …
Defining the risk of SARS-CoV-2 variants on immune protection
The global emergence of many severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants jeopardizes the protective antiviral immunity induced after infection or …
CoV-2) variants jeopardizes the protective antiviral immunity induced after infection or …
[HTML][HTML] mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron
M Gagne, JI Moliva, KE Foulds, SF Andrew, BJ Flynn… - Cell, 2022 - cell.com
SARS-CoV-2 Omicron is highly transmissible and has substantial resistance to
neutralization following immunization with ancestral spike-matched vaccines. It is unclear …
neutralization following immunization with ancestral spike-matched vaccines. It is unclear …
Protection against SARS-CoV-2 Beta variant in mRNA-1273 vaccine–boosted nonhuman primates
KS Corbett, M Gagne, DA Wagner, S O'Connell… - Science, 2021 - science.org
Neutralizing antibody responses gradually wane against several variants of concern (VOCs)
after vaccination with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
after vaccination with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
SARS-CoV-2 mRNA vaccination elicits robust antibody responses in children
Although children have been largely spared from coronavirus disease 2019 (COVID-19), the
emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of …
emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of …
Mucosal adenovirus vaccine boosting elicits IgA and durably prevents XBB. 1.16 infection in nonhuman primates
M Gagne, BJ Flynn, SF Andrew, J Marquez… - Nature …, 2024 - nature.com
A mucosal route of vaccination could prevent severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) replication at the site of infection and limit transmission. We …
coronavirus 2 (SARS-CoV-2) replication at the site of infection and limit transmission. We …
[HTML][HTML] Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in rhesus macaques coincides with anamnestic antibody response in the lung
M Gagne, KS Corbett, BJ Flynn, KE Foulds, DA Wagner… - Cell, 2022 - cell.com
Summary mRNA-1273 vaccine efficacy against SARS-CoV-2 Delta wanes over time;
however, there are limited data on the impact of durability of immune responses on …
however, there are limited data on the impact of durability of immune responses on …
The magnitude and timing of recalled immunity after breakthrough infection is shaped by SARS-CoV-2 variants
Vaccination against SARS-CoV-2 protects from infection and improves clinical outcomes in
breakthrough infections, likely reflecting residual vaccine-elicited immunity and recall of …
breakthrough infections, likely reflecting residual vaccine-elicited immunity and recall of …
Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques
Type I interferons (IFN-I) are critical mediators of innate control of viral infections but also
drive the recruitment of inflammatory cells to sites of infection, a key feature of severe …
drive the recruitment of inflammatory cells to sites of infection, a key feature of severe …
COVID-19 vaccines: current and future perspectives
L Soraci, F Lattanzio, G Soraci, ME Gambuzza… - Vaccines, 2022 - mdpi.com
Currently available vaccines against severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) are highly effective but not able to keep the coronavirus disease 2019 …
(SARS-CoV-2) are highly effective but not able to keep the coronavirus disease 2019 …