Mechanisms of immunothrombosis and vasculopathy in antiphospholipid syndrome

JS Knight, Y Kanthi - Seminars in immunopathology, 2022 - Springer
Antiphospholipid syndrome (APS) is an autoimmune thrombophilia propelled by circulating
antiphospholipid antibodies that herald vascular thrombosis and obstetrical complications …

Beta 2 glycoprotein I and neutrophil extracellular traps: potential bridge between innate and adaptive immunity in anti-phospholipid syndrome

C Grossi, N Capitani, M Benagiano, CT Baldari… - Frontiers in …, 2023 - frontiersin.org
Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by
recurrent vascular thrombosis and miscarriages in the absence of known causes. Antibodies …

[HTML][HTML] The role of neutrophil extracellular traps (NETs) in the pathogenesis of systemic lupus erythematosus and antiphospholipid syndrome

T Reshetnyak, K Nurbaeva - International journal of molecular sciences, 2023 - mdpi.com
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease of unknown
aetiology. It is characterized by impaired tolerance to a wide range of cellular and …

Application of the thrombin generation assay in patients with antiphospholipid syndrome: a systematic review of the literature

R Gehlen, A Vandevelde, B de Laat… - Frontiers in …, 2023 - frontiersin.org
Background The antiphospholipid syndrome (APS) is classified by the presence of
antiphospholipid antibodies (aPL) and thrombotic and/or adverse obstetric outcomes. The …

Antiphospholipid syndrome nephropathy: current knowledge and unanswered questions

E Xourgia, MG Tektonidou - Clinical Immunology, 2023 - Elsevier
The definition of acute and chronic antiphospholipid syndrome (APS) nephropathy was
recently updated using a multiphase methodology in the context of the development of the …

An update on inflammation in antiphospholipid syndrome

A Ambati, Y Zuo, JS Knight - Current opinion in rheumatology, 2023 - journals.lww.com
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Thrombin generation assay in antiphospholipid antibodies positive subjects as a personalized thrombotic risk assessment: state of the art and perspectives

T Foret, V Dufrost, J Lagrange, P Costa… - Current Rheumatology …, 2024 - Springer
Abstract Purpose of the Review Thrombotic risk assessment in antiphospholipid positive
(aPL+) subjects is a major challenge, and the study of in vitro thrombin generation (thrombin …

Augmented oxidative stress, accumulation of DNA damage and impaired DNA repair mechanisms in thrombotic primary antiphospholipid syndrome

M Pappa, PA Ntouros, C Papanikolaou, PP Sfikakis… - Clinical …, 2023 - Elsevier
Antiphospholipid syndrome (APS) is a rare autoimmune disorder with complex
pathogenesis. Studies have shown that oxidative stress may contribute to APS …

Research trends and frontiers on antiphospholipid syndrome: a 10-year bibliometric analysis (2012–2021)

T Wu, W Huang, J Qi, Y Li, Y Zhang, H Jiang… - Frontiers in …, 2022 - frontiersin.org
Objectives: A growing body of studies related to antiphospholipid syndrome (APS) have
been published in recent years. Nevertheless, there is a lack of visualized and systematic …

[HTML][HTML] An emerging role for Anti-DNA antibodies in systemic Lupus Erythematosus

T Kubota - International Journal of Molecular Sciences, 2023 - mdpi.com
Anti-DNA antibodies are hallmark autoantibodies produced in systemic lupus erythematosus
(SLE), but their pathogenetic role is not fully understood. Accumulating evidence suggests …