Objectives: Monitoring regional levels of transmitted HIV-1 resistance informs treatment
guidelines and provides feedback on the success of HIV-1 prevention efforts. Surveillance …

During the rapid spread of HIV-1 in humans, the main (M) group of HIV-1 has evolved into
ten distinct subtypes, undergone countless recombination events and diversified …

Background. A population-based phylogenetic approach was used to characterize human
immunodeficiency virus (HIV)—transmission dynamics in Quebec. Methods. HIV-1 pol …

Aims Review the current evidence regarding the prevalence of methamphetamine use
among men who have sex with men (MSM) and to evaluate the factors that contribute to …

Cell entry of enveloped viruses requires a wide-fusion-pore mechanism, involving clustering
of fusion-activated proteins and fluidization of the plasma membrane and viral envelope. In …

Highly active anti-retroviral therapy (HAART) is prescribed for HIV infection and, to a certain
extent, limits the infection's spread. However, it cannot completely eradicate the latent virus …

Perturbations of plasma IL-10, IL-12, IL-13, TNF-α, and IFN-γ were measured longitudinally
in HIV-1 seroconverting plasma donors and were compared to subjects with symptomatic …

Transmitted resistance to antiretroviral drugs in acute and early HIV-1 infection has been
well documented, although overall trends vary depending on geography and cohort …

HIV envelope glycoprotein transmembrane subunit gp41 plays a critical role in the fusion
between viral and target cell membranes. Upon gp120 binding to CD4 and a coreceptor …

The development of antiretroviral drugs over the past couple of decades has been
commendable owing to the identification of several new targets within the overall HIV …