Coronavirus pathogenesis

SR Weiss, JL Leibowitz - Advances in virus research, 2011 - pmc.ncbi.nlm.nih.gov
Coronaviruses infect many species of animals including humans, causing acute and chronic
diseases. This review focuses primarily on the pathogenesis of murine coronavirus mouse …

Accessory proteins of SARS-CoV and other coronaviruses

DX Liu, TS Fung, KKL Chong, A Shukla, R Hilgenfeld - Antiviral research, 2014 - Elsevier
The huge RNA genome of SARS coronavirus comprises a number of open reading frames
that code for a total of eight accessory proteins. Although none of these are essential for …

Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans

S Van Boheemen, M De Graaf, C Lauber… - MBio, 2012 - journals.asm.org
ABSTRACT A novel human coronavirus (HCoV-EMC/2012) was isolated from a man with
acute pneumonia and renal failure in June 2012. This report describes the complete …

The molecular biology of coronaviruses

PS Masters - Advances in virus research, 2006 - Elsevier
Coronaviruses are large, enveloped RNA viruses of both medical and veterinary
importance. Interest in this viral family has intensified in the past few years as a result of the …

Nidovirales: evolving the largest RNA virus genome

AE Gorbalenya, L Enjuanes, J Ziebuhr, EJ Snijder - Virus research, 2006 - Elsevier
This review focuses on the monophyletic group of animal RNA viruses united in the order
Nidovirales. The order includes the distantly related coronaviruses, toroviruses, and …

[HTML][HTML] Antagonism of the interferon-induced OAS-RNase L pathway by murine coronavirus ns2 protein is required for virus replication and liver pathology

L Zhao, BK Jha, A Wu, R Elliott, J Ziebuhr… - Cell host & …, 2012 - cell.com
Many viruses induce hepatitis in humans, highlighting the need to understand the
underlying mechanisms of virus-induced liver pathology. The murine coronavirus, mouse …

Utilization of glyphosate as phosphate source: biochemistry and genetics of bacterial carbon-phosphorus lyase

B Hove-Jensen, DL Zechel… - … and Molecular Biology …, 2014 - journals.asm.org
After several decades of use of glyphosate, the active ingredient in weed killers such as
Roundup, in fields, forests, and gardens, the biochemical pathway of transformation of …

Evolution and classification of P-loop kinases and related proteins

DD Leipe, EV Koonin, L Aravind - Journal of molecular biology, 2003 - Elsevier
Sequences and structures of all P-loop-fold proteins were compared with the aim of
reconstructing the principal events in the evolution of P-loop-containing kinases. It is shown …

Comparative genomics of the FtsK–HerA superfamily of pum** ATPases: implications for the origins of chromosome segregation, cell division and viral capsid …

LM Iyer, KS Makarova, EV Koonin… - Nucleic acids …, 2004 - academic.oup.com
Recently, it has been shown that a predicted P-loop ATPase (the HerA or MlaA protein),
which is highly conserved in archaea and also present in many bacteria but absent in …

Evolutionary history of the closely related group 2 coronaviruses: porcine hemagglutinating encephalomyelitis virus, bovine coronavirus, and human coronavirus …

L Vijgen, E Keyaerts, P Lemey, P Maes… - Journal of …, 2006 - journals.asm.org
The close genetic and antigenic relatedness among the group 2 coronaviruses human
coronavirus OC43 (HCoV-OC43), bovine coronavirus (BCoV), and porcine …