Pharmacokinetics of magnetic iron oxide nanoparticles for medical applications

J Nowak-Jary, B Machnicka - Journal of Nanobiotechnology, 2022 - Springer
Magnetic iron oxide nanoparticles (MNPs) have been under intense investigation for at least
the last five decades as they show enormous potential for many biomedical applications …

Design strategies for shape-controlled magnetic iron oxide nanoparticles

AG Roca, L Gutiérrez, H Gavilán, MEF Brollo… - Advanced drug delivery …, 2019 - Elsevier
Ferrimagnetic iron oxide nanoparticles (magnetite or maghemite) have been the subject of
an intense research, not only for fundamental research but also for their potentiality in a …

Environmental implications and applications of engineered nanoscale magnetite and its hybrid nanocomposites: A review of recent literature

C Su - Journal of hazardous materials, 2017 - Elsevier
This review focuses on environmental implications and applications of engineered
magnetite (Fe 3 O 4) nanoparticles (MNPs) as a single phase or a component of a hybrid …

Long-term fate of magnetic particles in mice: A comprehensive study

IV Zelepukin, AV Yaremenko, IN Ivanov, MV Yuryev… - ACS …, 2021 - ACS Publications
Safe application of nanoparticles in medicine requires full understanding of their
pharmacokinetics including catabolism in the organism. However, information about …

Principles of magnetic hyperthermia: a focus on using multifunctional hybrid magnetic nanoparticles

IM Obaidat, V Narayanaswamy, S Alaabed… - Magnetochemistry, 2019 - mdpi.com
Hyperthermia is a noninvasive method that uses heat for cancer therapy where high
temperatures have a damaging effect on tumor cells. However, large amounts of heat need …

Massive intracellular biodegradation of iron oxide nanoparticles evidenced magnetically at single-endosome and tissue levels

F Mazuel, A Espinosa, N Luciani, M Reffay… - ACS …, 2016 - ACS Publications
Quantitative studies of the long-term fate of iron oxide nanoparticles inside cells, a
prerequisite for regenerative medicine applications, are hampered by the lack of suitable …

Effect of surface chemistry and associated protein corona on the long-term biodegradation of iron oxide nanoparticles in vivo

G Stepien, M Moros, M Pérez-Hernández… - … applied materials & …, 2018 - ACS Publications
The protein corona formed on the surface of a nanoparticle in a biological medium
determines its behavior in vivo. Herein, iron oxide nanoparticles containing the same core …

Aggregation effects on the magnetic properties of iron oxide colloids

L Gutiérrez, L De la Cueva, M Moros, E Mazarío… - …, 2019 - iopscience.iop.org
Magnetic nanoparticles (MNPs), and in particular iron oxide nanoparticles (mainly magnetite
and maghemite), are being widely used in the form of aqueous colloids for biomedical …

Biosynthesis of magnetic nanoparticles from nano-degradation products revealed in human stem cells

A Van de Walle, A Plan Sangnier… - Proceedings of the …, 2019 - National Acad Sciences
While magnetic nanoparticles offer exciting possibilities for stem cell imaging or tissue
bioengineering, their long-term intracellular fate remains to be fully documented. Besides, it …

Different coatings on magnetic nanoparticles dictate their degradation kinetics in vivo for 15 months after intravenous administration in mice

Y Portilla, Y Fernández-Afonso, S Pérez-Yagüe… - Journal of …, 2022 - Springer
Background The surface coating of iron oxide magnetic nanoparticle (MNPs) drives their
intracellular trafficking and degradation in endolysosomes, as well as dictating other cellular …