Objectives The reference standard methods for drug susceptibility testing (DST) of M.
tuberculosis are very slow to give results, and due to the emergence of multidrug-resistant …

Background New diagnostic tools are urgently needed to interrupt the transmission of
tuberculosis and multidrug-resistant tuberculosis. Rapid, sensitive detection of tuberculosis …

The rising number of resistant and multidrug-resistant Mycobacterium tuberculosis strains
and the emergence of extensively drug-resistant strains substantiate the urgent demand for …

The EmbCAB proteins have been considered a target for ethambutol (EMB). Mutations in
embCAB are known to confer most EMB resistance. However, the knowledge about the …

In this study, we describe the antimycobacterial activity of two pigments, violacein, a purple
violet pigment from Janthinobacterium sp. Ant5-2 (J-PVP), and flexirubin, a yellow-orange …

In the present study, the effectiveness of a rapid and colorimetric nitrate reductase analysis
(NRA) method and resazurin microplate assay (REMA) for rapid determination of methicillin …

The intersample and intrasample variability of the results obtained with the microplate
Alamar blue assay for the indirect drug susceptibility testing of Mycobacterium tuberculosis …

Several new methods to detect drug resistance in Mycobacterium tuberculosis have been
proposed in recent years. Colourimetric methods that use redox indicators or the nitrate …

Microbial multidrug resistance (MDR) poses a huge threat to human health. Bacterial
acquisition of MDR relies primarily on class 1 integron-involved horizontal gene transfer …

The identification of Mycobacterium tuberculosis genes, specifically expressed during
infection is a key step in understanding molecular mechanism of mycobacterial …