Berberine and its study as an antidiabetic compound

AR Utami, IP Maksum, Y Deawati - Biology, 2023 - mdpi.com
Simple Summary Glucose is needed as the main source of energy in the body. However, too
high sugar levels can lead to a variety of serious complications, including with the …

General toxicity studies of alpha mangostin from Garcinia mangostana: A systematic review

LU Setyawati, W Nurhidayah, NKK Ikram, WEM Fuad… - Heliyon, 2023 - cell.com
Alpha mangostin (AM), the main xanthone derivative contained in mangosteen pericarp
(Garcinia mangostana/GM), has many pharmacological activities such as antioxidant …

[HTML][HTML] Phytobioinformatics screening of ayurvedic plants for potential α-glucosidase inhibitors in diabetes management

H Khalid, MH Butt, I Ahmad, F Iqbal, A Shamim… - Current Plant …, 2024 - Elsevier
The enzyme α-glucosidase in the small intestine regulates blood glucose levels and
stimulates the hydrolysis of oligosaccharides and polysaccharides, increasing glucose …

[HTML][HTML] Antimicrobial, Cytotoxic, and α-Glucosidase Inhibitory Activities of Ethanol Extract and Chemical Constituents Isolated from Homotrigona apicalis Propolis …

DTL Phuong, N Van Phuong, N Le Tuan, NT Cong… - Life, 2023 - mdpi.com
The chemical investigation of Homotrigona apicalis propolis collected in Binh Dinh province,
Vietnam, led to the isolation of nine compounds, including four sesquiterpenes: spathulenol …

Updating the Pharmacological Effects of α-Mangostin Compound and Unraveling Its Mechanism of Action: A Computational Study Review

C Suhandi, G Wilar, AC Narsa… - Drug Design …, 2024 - Taylor & Francis
Abstract α-Mangostin, initially identified in 1855, is a xanthone derivative compound
predominantly located in the pericarp of the mangosteen fruit (Garcinia mangostana L). This …

[HTML][HTML] Natural selection of Lacticaseibacillus paracasei mutant: weaken the post-acidification of fermented milk

L Li, H Lu, Y Xue, Y He, B Zhao, L Ai, S Wang - Food Bioscience, 2025 - Elsevier
Probiotic fermented milk has emerged as a prominent functional food for its substantial role
in promoting intestinal health and overall wellness. However, a persistent challenge in the …

In Silico Exploration of Isoxazole Derivatives of Usnic Acid: Novel Therapeutic Prospects Against α-Amylase for Diabetes Treatment

M Roney, AR Issahaku, AKMM Huq, S Sapari… - Cell Biochemistry and …, 2024 - Springer
Diabetes mellitus (DM) a metabolic disorder characterized by high blood sugar levels
causing damage to various organs over time. Current anti-diabetic drugs have limitations …

Insights from in silico exploration of major curcumin analogs targeting human dipeptidyl peptidase IV

M Roney, A Dubey, AR Issahaku… - Journal of …, 2024 - Taylor & Francis
The goal of this work is to use a variety of in-silico techniques to identify anti-diabetic agents
against DPP-IV enzyme from five main curcumin analogues. To produce the successful …

Mechanistic study of α-mangostin derivatives as potent α-glucosidase inhibitors

K Sanachai, S Chamni, B Nutho, S Khammuang… - Molecular Diversity, 2025 - Springer
Abstract α-Glucosidase inhibitors (AGIs) are pharmacological agents commonly used to
manage postprandial hyperglycemia associated with type 2 diabetes mellitus (T2DM) …

[PDF][PDF] Phytobioinformatics screening of ayurvedic plants for potential α-glucosidase inhibitors in diabetes management

F Iqbal, A Shamim, U Nishan, R Ullah… - Current Plant …, 2024 - researchgate.net
The enzyme α-glucosidase in the small intestine regulates blood glucose levels and
stimulates the hydrolysis of oligosaccharides and polysaccharides, increasing glucose …