[HTML][HTML] Sex hormone fluctuation and increased female risk for depression and anxiety disorders: From clinical evidence to molecular mechanisms

M Kundakovic, D Rocks - Frontiers in neuroendocrinology, 2022 - Elsevier
Women are at twice the risk for anxiety and depression disorders as men are, although the
underlying biological factors and mechanisms are largely unknown. In this review, we …

The menopause transition: signs, symptoms, and management options

N Santoro, C Roeca, BA Peters… - The Journal of Clinical …, 2021 - academic.oup.com
Context Menopause, the permanent cessation of menses, reflects oocyte depletion and loss
of gonadal steroids. It is preceded by a transition state, the perimenopause, which is …

Best practices for stress measurement: How to measure psychological stress in health research

AD Crosswell, KG Lockwood - Health psychology open, 2020 - journals.sagepub.com
Despite the strong evidence linking psychological stress to disease risk, health researchers
often fail to include psychological stress in models of health. One reason for this is the …

Symptoms of menopause—global prevalence, physiology and implications

P Monteleone, G Mascagni, A Giannini… - Nature Reviews …, 2018 - nature.com
The symptoms of menopause can be distressing, particularly as they occur at a time when
women have important roles in society, within the family and at the workplace. Hormonal …

Why is depression more common among women than among men?

C Kuehner - The lancet psychiatry, 2017 - thelancet.com
Women are about twice as likely as are men to develop depression during their lifetime. This
Series paper summarises evidence regarding the epidemiology on gender differences in …

Stress, sex hormones, inflammation, and major depressive disorder: Extending Social Signal Transduction Theory of Depression to account for sex differences in …

GM Slavich, J Sacher - Psychopharmacology, 2019 - Springer
Abstract Social Signal Transduction Theory of Depression is a biologically plausible, multi-
level theory that describes neural, physiologic, molecular, and genomic mechanisms that …

The role of the hypothalamic-pituitary-adrenal axis in depression across the female reproductive lifecycle: current knowledge and future directions

L Hantsoo, KM Jagodnik, AM Novick… - Frontiers in …, 2023 - frontiersin.org
The aim of this narrative review is to consolidate knowledge on the role of the hypothalamic-
pituitary-adrenal (HPA) axis in depression pathophysiology at different reproductive stages …

Sex and gender driven modifiers of Alzheimer's: the role for estrogenic control across age, race, medical, and lifestyle risks

A Rahman, H Jackson, H Hristov… - Frontiers in aging …, 2019 - frontiersin.org
Research indicates that after advanced age, the major risk factor for late-onset Alzheimer's
disease (AD) is female sex. Out of every three AD patients, two are females with …

Efficacy of transdermal estradiol and micronized progesterone in the prevention of depressive symptoms in the menopause transition: a randomized clinical trial

JL Gordon, DR Rubinow, TA Eisenlohr-Moul… - JAMA …, 2018 - jamanetwork.com
Importance The menopause transition and early postmenopausal period are associated with
a 2-to 4-fold increased risk for clinically significant depressive symptoms. Although a few …

Population-based cohort study of oral contraceptive use and risk of depression

T Johansson, SV Larsen, M Bui, WE Ek… - Epidemiology and …, 2023 - cambridge.org
AimResearch on the effect of oral contraceptive (OC) use on the risk of depression shows
inconsistent findings, especially in adult OC users. One possible reason for this …