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Stress to inflammation and anhedonia: Mechanistic insights from preclinical and clinical models
Anhedonia, as evidenced by impaired pleasurable response to reward, reduced reward
motivation, and/or deficits in reward-related learning, is a common feature of depression …
motivation, and/or deficits in reward-related learning, is a common feature of depression …
Astrocyte regulation of synaptic signaling in psychiatric disorders
Over the last 15 years, the field of neuroscience has evolved toward recognizing the critical
role of astroglia in sha** neuronal synaptic activity and along with the pre-and …
role of astroglia in sha** neuronal synaptic activity and along with the pre-and …
[HTML][HTML] Dissection of the relationship between anxiety and stereotyped self-grooming using the Shank3B mutant autistic model, acute stress model and chronic pain …
H Liu, X Huang, J Xu, H Mao, Y Li, K Ren, G Ma… - Neurobiology of …, 2021 - Elsevier
Self-grooming is an innate, cephalo-caudal progression of body cleaning behaviors that are
found in normal rodents but exhibit repetitive and stereotyped patterns in several mouse …
found in normal rodents but exhibit repetitive and stereotyped patterns in several mouse …
Post-traumatic stress disorder: focus on neuroinflammation
J Li, L Tong, BC Schock, LL Ji - Molecular Neurobiology, 2023 - Springer
Post-traumatic stress disorder (PTSD), gaining increasing attention, is a multifaceted
psychiatric disorder that occurs following a stressful or traumatic event or series of events …
psychiatric disorder that occurs following a stressful or traumatic event or series of events …
Intrusive thinking: Circuit and synaptic mechanisms of a transdiagnostic psychiatric symptom
Spontaneous thought is an adaptive cognitive process that can produce novel and insightful
thought sequences useful in guiding future behavior. In many psychiatric disorders …
thought sequences useful in guiding future behavior. In many psychiatric disorders …
Repeated binge‐like eating episodes in female rats alter adenosine A2A and dopamine D2 receptor genes regulation in the brain reward system
F Mercante, E Micioni Di Bonaventura… - … Journal of Eating …, 2024 - Wiley Online Library
Objective Binge‐eating disorder is an eating disorder characterized by recurrent binge‐
eating episodes, during which individuals consume excessive amounts of highly palatable …
eating episodes, during which individuals consume excessive amounts of highly palatable …
(2R, 6R)-hydroxynorketamine improves PTSD-associated behaviors and structural plasticity via modulating BDNF-mTOR signaling in the nucleus accumbens
L Gou, Y Li, S Liu, H Sang, J Lan, J Chen… - Journal of Affective …, 2023 - Elsevier
Background Post-traumatic stress disorder (PTSD) is a mental illness caused by either
experiencing or observing a traumatic event that is perceived to pose a serious risk to one's …
experiencing or observing a traumatic event that is perceived to pose a serious risk to one's …
Inhibition of mGluR5 alters BDNF/TrkB and GLT-1 expression in the prefrontal cortex and hippocampus and ameliorates PTSD-like behavior in rats
S Cheng, J Xu, W Wang, R Wang, H Li, Z Jiang… - …, 2023 - Springer
Rationale and objective Post-traumatic stress disorder (PTSD) is a prevalent and debilitating
psychiatric disorder. However, its specific etiological mechanism remains unclear. Previous …
psychiatric disorder. However, its specific etiological mechanism remains unclear. Previous …
[HTML][HTML] Beyond the neuron: Role of non-neuronal cells in stress disorders
Stress disorders are leading causes of disease burden in the US and worldwide, yet
available therapies are fully effective in less than half of all individuals with these disorders …
available therapies are fully effective in less than half of all individuals with these disorders …
Deficiency of Tet3 in nucleus accumbens enhances fear generalization and anxiety‐like behaviors in mice
BF Fan, B Hao, YD Dai, L Xue, YW Shi, L Liu… - Brain …, 2022 - Wiley Online Library
Stress‐induced neuroepigenetic programming gains growing more and more interest in the
studies of the etiology of posttraumatic stress disorder (PTSD). However, seldom attention is …
studies of the etiology of posttraumatic stress disorder (PTSD). However, seldom attention is …