Neurological soft signs as candidate endophenotypes for schizophrenia: a shooting star or a Northern star?

RCK Chan, II Gottesman - Neuroscience & Biobehavioral Reviews, 2008‏ - Elsevier
The crucial role of neurological indicators in schizophrenia has been recognized as among
the “target features” that encompass the idea that genetic and non-genetic processes lead to …

Genetics and intermediate phenotypes of the schizophrenia—bipolar disorder boundary

EI Ivleva, DW Morris, AF Moates, T Suppes… - Neuroscience & …, 2010‏ - Elsevier
Categorization of psychotic illnesses into schizophrenic and affective psychoses remains an
ongoing controversy. Although Kraepelinian subty** of psychosis was historically …

Brain regions and genes affecting limb-clas** responses

R Lalonde, C Strazielle - Brain research reviews, 2011‏ - Elsevier
Adult rodents picked up by the tail and slowly descending towards a horizontal surface
extend all four limbs in anticipation of contact. Mouse mutants with pathologies in various …

Motor dysfunction as research domain in the period preceding manifest schizophrenia: a systematic review

D Hirjak, A Meyer-Lindenberg, KM Kubera… - Neuroscience & …, 2018‏ - Elsevier
Schizophrenia is a severe behavioral syndrome of neurodevelopmental nature marked by
primary or genuine motor abnormalities (GMA), which refer to spontaneous and medication …

To cut a short test even shorter: reliability and validity of a brief assessment of intellectual ability in schizophrenia—a control-case family study

E Velthorst, SZ Levine, C Henquet… - Cognitive …, 2013‏ - Taylor & Francis
Background. The potential inclusion of cognitive assessments in the DSM-V and large time-
consuming assessments drive a need for short tests of cognitive impairments. We examined …

Neurological soft signs in schizophrenia: an update on the state-versus trait-perspective

S Bachmann, J Schröder - Frontiers in psychiatry, 2018‏ - frontiersin.org
Background Neurological soft signs (NSS) represent minor neurological signs, which
indicate non-specific cerebral dysfunction. In schizophrenia, their presence has been …

Premorbid cognitive deficits in young relatives of schizophrenia patients

MS Keshavan, SR Kulkarni, T Bhojraj… - Frontiers in human …, 2010‏ - frontiersin.org
Neurocognitive deficits in schizophrenia are thought to be stable trait markers that predate
the illness and manifest in relatives of patients. Adolescence is the age of maximum …

A systematic review and meta-analysis of neurological soft signs in relatives of people with schizophrenia

K Neelam, D Garg, M Marshall - BMC psychiatry, 2011‏ - Springer
Background Neurological soft signs are subtle but observable impairments in motor and
sensory functions that are not localized to a specific area of the brain. Neurological soft signs …

A neural signature of parkinsonism in patients with schizophrenia spectrum disorders: a multimodal MRI study using parallel ICA

RC Wolf, M Rashidi, S Fritze, KM Kubera… - Schizophrenia …, 2020‏ - academic.oup.com
Motor abnormalities in schizophrenia spectrum disorders (SSD) have increasingly attracted
scientific interest in the past years. However, the neural mechanisms underlying …

[HTML][HTML] Primitive reflexes

AK Modrell, P Tadi - StatPearls [Internet], 2023‏ - ncbi.nlm.nih.gov
Primitive reflexes are involuntary motor responses originating in the brainstem present after
birth in early child development that facilitate survival. Several reflexes are important in the …