Phenol-directed C–H functionalization
Phenols are important starting materials, intermediates, and functional elements of a very
broad range of chemicals and materials. They are large-volume products of benzene …
broad range of chemicals and materials. They are large-volume products of benzene …
Transition-metal-catalyzed ortho-selective C–H functionalization reactions of free phenols
Phenols are important readily available chemical feedstocks and versatile synthetic building
blocks for diverse synthetic transformations. Their motifs are prevalent in a diverse array of …
blocks for diverse synthetic transformations. Their motifs are prevalent in a diverse array of …
Csp 2–H functionalization of phenols: an effective access route to valuable materials via Csp 2–C bond formation
In the vast majority of top-selling pharmaceutical and industrial products, phenolic structural
motifs are highly prevalent. Non-functionalized simple phenols serve as building blocks in …
motifs are highly prevalent. Non-functionalized simple phenols serve as building blocks in …
Free Amine and Alcohol As the Director for Regioselective C(sp2)–H Bond Functionalization
Transition-metal-catalyzed C (sp2)–H bond functionalization is recognized as a
revolutionized strategy for mainstream organic synthesis to forge structurally complex …
revolutionized strategy for mainstream organic synthesis to forge structurally complex …
Selective Modular Synthesis of ortho-Substituted Phenols via Pd-Catalyzed Dehydrogenation–Coupling–Aromatization of Alcohols
G Zeng, L Shen, Q Zheng, T Tu - ACS Catalysis, 2023 - ACS Publications
Phenols are pivotal precursors and core motifs for various fine chemicals, bioactive
molecules, and functional materials, among which the site-selective syntheses of ortho …
molecules, and functional materials, among which the site-selective syntheses of ortho …
Isotope Effects Reveal the Catalytic Mechanism of the Archetypical Suzuki-Miyaura Reaction
Experimental and theoretical 13C kinetic isotope effects (KIEs) are utilized to obtain
atomistic insight into the catalytic mechanism of the Pd (PPh3) 4-catalyzed Suzuki-Miyaura …
atomistic insight into the catalytic mechanism of the Pd (PPh3) 4-catalyzed Suzuki-Miyaura …
Ruthenium-Catalyzed C–F Bond Arylation of Polyfluoroarenes: Polyfluorinated Biaryls by Integrated C–F/C–H Functionalization
J Zhang, J Liu, X Wang, X Yang, Y Ma, R Fang… - ACS …, 2022 - ACS Publications
Fluorine-containing molecules are central motifs in pharmaceuticals, agrochemicals, and
functional materials owing to the unique properties engendered by carbon–fluorine bonds …
functional materials owing to the unique properties engendered by carbon–fluorine bonds …
Dearomatization‐Rearomatization Strategy for ortho‐Selective Alkylation of Phenols with Primary Alcohols
Phenols are common precursors and core structures of a variety of industrial chemicals
ranging from pharmaceuticals to polymers. However, the synthesis of site‐specifically …
ranging from pharmaceuticals to polymers. However, the synthesis of site‐specifically …
Experimental and Computational Studies on the Ruthenium-Catalyzed Dehydrative C–H Coupling of Phenols with Aldehydes for the Synthesis of 2-Alkylphenol …
The cationic Ru–H complex [(C6H6)(PCy3)(CO) RuH]+ BF4–(1) was found to be an effective
catalyst for the dehydrative C–H coupling reaction of phenols and aldehydes to form 2 …
catalyst for the dehydrative C–H coupling reaction of phenols and aldehydes to form 2 …
One-Pot Tandem Access to Phenothiazine Derivatives from Acetanilide and 2-Bromothiophenol via Rhodium-Catalyzed C–H Thiolation and Copper-Catalyzed C–N …
X Rui, C Wang, D Si, X Hui, K Li, H Wen… - The Journal of Organic …, 2021 - ACS Publications
A one-pot and step economic reaction involving Rh (III)-catalyzed C–H thiolation and relay
Cu (II)-catalyzed C–N amination of acetanilide and 2-bromothiophenol is reported here, with …
Cu (II)-catalyzed C–N amination of acetanilide and 2-bromothiophenol is reported here, with …