The emerging tale of microglia in psychiatric disorders

R Rahimian, M Wakid, LA O'Leary… - … & Biobehavioral Reviews, 2021 - Elsevier
As the professional phagocytes of the brain, microglia orchestrate the immunological
response and play an increasingly important role in maintaining homeostatic brain functions …

Methamphetamine: Effects on the brain, gut and immune system

MD Prakash, K Tangalakis, J Antonipillai… - Pharmacological …, 2017 - Elsevier
Methamphetamine (METH) is a powerful central nervous system stimulant which elevates
mood, alertness, energy levels and concentration in the short-term. However, chronic use …

Neuroinflammation in addiction: A review of neuroimaging studies and potential immunotherapies

M Kohno, J Link, LE Dennis, H McCready… - Pharmacology …, 2019 - Elsevier
Addiction is a worldwide public health problem and this article reviews scientific advances in
identifying the role of neuroinflammation in the genesis, maintenance, and treatment of …

[HTML][HTML] Crosstalk between Mu-Opioid receptors and neuroinflammation: Consequences for drug addiction and pain

J Cuitavi, JV Torres-Pérez, JD Lorente… - Neuroscience & …, 2023 - Elsevier
Abstract Mu-Opioid Receptors (MORs) are well-known for participating in analgesia,
sedation, drug addiction, and other physiological functions. Although MORs have been …

Methamphetamine neurotoxicity, microglia, and neuroinflammation

F Shaerzadeh, WJ Streit, S Heysieattalab… - Journal of …, 2018 - Springer
Methamphetamine (METH) is an illicit psychostimulant that is subject to abuse worldwide.
While the modulatory effects of METH on dopamine neurotransmission and its neurotoxicity …

Methamphetamine-induced neuronal damage: neurotoxicity and neuroinflammation

B Kim, J Yun, B Park - Biomolecules & therapeutics, 2020 - pmc.ncbi.nlm.nih.gov
Methamphetamine (METH) is a highly addictive psychostimulant and one of the most widely
abused drugs worldwide. The continuous use of METH eventually leads to drug addiction …

Protective role of metformin against methamphetamine induced anxiety, depression, cognition impairment and neurodegeneration in rat: the role of CREB/BDNF and …

S Keshavarzi, S Kermanshahi, L Karami… - Neurotoxicology, 2019 - Elsevier
Background Methamphetamine is a neuro-stimulant with neurodegenerative effects, and
ambiguous mechanism of action. Metformin is an antidiabetic agent with neuroprotective …

Drugs of abuse and blood-brain barrier endothelial dysfunction: A focus on the role of oxidative stress

RK Sajja, S Rahman, L Cucullo - Journal of Cerebral Blood …, 2016 - journals.sagepub.com
Psychostimulants and nicotine are the most widely abused drugs with a detrimental impact
on public health globally. While the long-term neurobehavioral deficits and synaptic …