Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis
AS Nagle, S Khare, AB Kumar, F Supek… - Chemical …, 2014 - ACS Publications
Leishmaniasis is a parasitic disease that presents four main clinical syndromes: cutaneous
leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), visceral leishmaniasis/kala azar …
leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), visceral leishmaniasis/kala azar …
[PDF][PDF] The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II
TJ Schmidt, SA Khalid, AJ Romanha, TMA Alves… - 2012 - researchgate.net
Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …
[HTML][HTML] Syzygium cumini (L.) Skeels essential oil and its major constituent α-pinene exhibit anti-Leishmania activity through immunomodulation in vitro
Ethnopharmacological relevance Syzygium cumini (L.) Skeels (Myrtaceae), commonly
known as “jambolão” in Brazil is widely used in folk medicine against leishmaniasis …
known as “jambolão” in Brazil is widely used in folk medicine against leishmaniasis …
Plant derived therapeutics for the treatment of Leishmaniasis
Diseases caused by insect borne trypanosomatid parasites are significant, yet remain a
neglected public health problem. Leishmania, a unicellular protozoan parasite is the …
neglected public health problem. Leishmania, a unicellular protozoan parasite is the …
Fruitful decade for antileishmanial compounds from 2002 to late 2011
Leishmaniasis, usually caused by the genus Leishmania, has not received the attention it
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …
A review of the antimalarial, antitrypanosomal, and antileishmanial activities of natural compounds isolated from Nigerian flora
The West African country Nigeria features highly diverse vegetation and climatic conditions
that range from rain forest bordering the Atlantic Ocean in the South to the Desert (Sahara) …
that range from rain forest bordering the Atlantic Ocean in the South to the Desert (Sahara) …
A review on new natural and synthetic anti-leishmanial chemotherapeutic agents and current perspective of treatment approaches.
N Majumder, A Banerjee, S Saha - Acta Tropica, 2023 - Elsevier
Leishmaniases are considered among the most neglected yet dangerous parasitic diseases
worldwide. According to the recent WHO report (Weekly Epidemiological Record, Sep …
worldwide. According to the recent WHO report (Weekly Epidemiological Record, Sep …
Constructing Quaternary Stereogenic Centers Using Tertiary Organocuprates and Tertiary Radicals. Total Synthesis of trans-Clerodane Natural Products
DS Müller, NL Untiedt, AP Dieskau… - Journal of the …, 2015 - ACS Publications
A new concise construction of trans-clerodane diterpenoids is reported in which oxacyclic
and trans-hydronaphthalene fragments are coupled, and the critical C9-quaternary carbon …
and trans-hydronaphthalene fragments are coupled, and the critical C9-quaternary carbon …
Induction of mitochondrial dysfunction and oxidative stress in Leishmania donovani by orally active clerodane diterpene
M Kathuria, A Bhattacharjee… - Antimicrobial agents …, 2014 - Am Soc Microbiol
This study was performed to investigate the mechanistic aspects of cell death induced by a
clerodane diterpene (K-09) in Leishmania donovani promastigotes that was previously …
clerodane diterpene (K-09) in Leishmania donovani promastigotes that was previously …
Plants as antileishmanial agents: current scenario
Leishmaniasis is a clinical manifestation caused by the parasites of the genus Leishmania.
Plants are reservoirs of bioactive compounds, which are known to be chemically balanced …
Plants are reservoirs of bioactive compounds, which are known to be chemically balanced …