Epidemiology and pathogenesis of ulcerative colitis

L Du, C Ha - Gastroenterology Clinics, 2020 - gastro.theclinics.com
Ulcerative colitis (UC) is a chronic immune-mediated inflammatory disorder of the colon
(IBD) that is hypothesized to be related to exposure to environmental risk factors leading to …

Inflammatory bowel disease presentation and diagnosis

S Flynn, S Eisenstein - Surgical Clinics, 2019 - surgical.theclinics.com
Inflammatory bowel disease (IBD) is the continuum of diseases that comprise Crohn's
disease (CD), ulcerative colitis (UC), and indeterminate colitis. The incidence of IBD has …

Mechanisms of disease: inflammatory bowel diseases

GP Ramos, KA Papadakis - Mayo Clinic Proceedings, 2019 - Elsevier
Inflammatory bowel diseases (IBDs), represented by Crohn disease and ulcerative colitis,
are associated with major morbidity in Western countries and with increasing incidence in …

Potential role of flavonoids in treating chronic inflammatory diseases with a special focus on the anti-inflammatory activity of apigenin

R Ginwala, R Bhavsar, DGI Chigbu, P Jain, ZK Khan - Antioxidants, 2019 - mdpi.com
Inflammation has been reported to be intimately linked to the development or worsening of
several non-infectious diseases. A number of chronic conditions such as cancer, diabetes …

[HTML][HTML] Single-cell analysis of Crohn's disease lesions identifies a pathogenic cellular module associated with resistance to anti-TNF therapy

JC Martin, C Chang, G Boschetti, R Ungaro, M Giri… - Cell, 2019 - cell.com
Clinical benefits of cytokine blockade in ileal Crohn's disease (iCD) are limited to a subset of
patients. Here, we applied single-cell technologies to iCD lesions to address whether …

[HTML][HTML] The role of innate and adaptive immune cells in the pathogenesis and development of the inflammatory response in ulcerative colitis

A Kałużna, P Olczyk, K Komosińska-Vassev - Journal of clinical medicine, 2022 - mdpi.com
Ulcerative colitis (UC) is a chronic inflammatory disease with an underlying excessive
immune response directed against resident microbiota and/or dietary antigens. Both innate …

Immunopathogenesis of IBD: current state of the art

HSP De Souza, C Fiocchi - Nature reviews Gastroenterology & …, 2016 - nature.com
IBD is a chronic inflammatory condition of the gastrointestinal tract encompassing two main
clinical entities: Crohn's disease and ulcerative colitis. Although Crohn's disease and …

Immunology of inflammatory bowel disease: molecular mechanisms and therapeutics

Q Lu, M Yang, Y Liang, J Xu, H Xu, Y Nie… - Journal of …, 2022 - Taylor & Francis
As a main digestive organ and an important immune organ, the intestine plays a vital role in
resisting the invasion of potential pathogens into the body. Intestinal immune dysfunction …

Pathophysiology of inflammatory bowel disease: innate immune system

A Saez, B Herrero-Fernandez, R Gomez-Bris… - International Journal of …, 2023 - mdpi.com
Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis
(UC), is a heterogeneous state of chronic intestinal inflammation with no exact known cause …

Immune response and inflammatory pathway of ulcerative colitis

N Tatiya-Aphiradee, W Chatuphonprasert… - Journal of basic and …, 2019 - degruyter.com
Ulcerative colitis (UC) is an idiopathic relapsing inflammatory disease. Although the etiology
of UC remains unclear, it could be characterized by inflammation of the intestinal mucosa …