The hidden island of addiction: the insula

NH Naqvi, A Bechara - Trends in neurosciences, 2009 - cell.com
Most prior research on the neurobiology of addiction has focused on the role of subcortical
systems, such as the amygdala, the ventral striatum and mesolimbic dopamine system, in …

Brain imaging approaches to the study of functional GI disorders: a Rome working team report

EA Mayer, Q Aziz, S Coen, M Kern… - …, 2009 - Wiley Online Library
Progresses in the understanding of human brain‐gut interactions in health and disease
have been limited by the lack of non‐invasive techniques to study brain activity. The advent …

Functional neuroanatomy of the insular lobe

C Stephani, G Fernandez-Baca Vaca… - Brain structure and …, 2011 - Springer
The insula is the fifth lobe of the brain and it is the least known. Hidden under the temporal,
frontal and parietal opercula, as well as under dense arterial and venous vessels, its …

Gastric distention activates satiety circuitry in the human brain

GJ Wang, D Tomasi, W Backus, R Wang, F Telang… - Neuroimage, 2008 - Elsevier
Gastric distention during meal ingestion activates vagal afferents, which send signals from
the stomach to the brain and result in the perception of fullness and satiety. Distention is one …

[KÖNYV][B] Nausea: mechanisms and management

RM Stern, KL Koch, P Andrews - 2011 - books.google.com
Nausea is a complex sensation that results from the interaction of certain fixed biological
factors, such as gender, with changeable psychological factors, such as anxiety. This is the …

Abnormal regional brain activity during rest and (anticipated) gastric distension in functional dyspepsia and the role of anxiety: a H215O-PET study

L Van Oudenhove, J Vandenberghe… - Official journal of the …, 2010 - journals.lww.com
OBJECTIVES: During gastric distension in hypersensitive functional dyspepsia (FD),
activation was found in somatosensory cortex (SI/SII) and ventrolateral prefrontal cortex …

The stomach–brain axis

G Holtmann, NJ Talley - Best Practice & Research Clinical …, 2014 - Elsevier
The stomach has distinct functions in relation to the ingestion and handling of solids and
liquids. These functions include storage of the food before it is gradually emptied into the …

Regional brain activity in functional dyspepsia: a H215O-PET study on the role of gastric sensitivity and abuse history

L Van Oudenhove, J Vandenberghe, P Dupont… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Differences in brain activity between health and functional
dyspepsia (FD) have been reported; it is unclear whether this is influenced by gastric …

Map** of brain activations to rectal balloon distension stimuli in male patients with irritable bowel syndrome using functional magnetic resonance imaging

A Guleria, A Karyampudi, R Singh… - Journal of …, 2017 - pmc.ncbi.nlm.nih.gov
Background/Aims Irritable bowel syndrome (IBS) is associated with exaggerated cerebral
response including emotional processing following visceral stimulation; though data on this …

Uncertainty in anticipation of uncomfortable rectal distension is modulated by the autonomic nervous system—a fMRI study in healthy volunteers

A Rubio, L Van Oudenhove, S Pellissier, HG Ly… - Neuroimage, 2015 - Elsevier
The human brain responds both before and during the application of aversive stimuli.
Anticipation allows the organism to prepare its nociceptive system to respond adequately to …