Antimicrobial resistance monitoring of water environments: a framework for standardized methods and quality control

K Liguori, I Keenum, BC Davis, J Calarco… - … science & technology, 2022 - ACS Publications
Antimicrobial resistance (AMR) is a grand societal challenge with important dimensions in
the water environment that contribute to its evolution and spread. Environmental monitoring …

[HTML][HTML] Environmental antimicrobial resistance and its drivers: a potential threat to public health

I Ahmad, HA Malak, HH Abulreesh - Journal of Global Antimicrobial …, 2021 - Elsevier
Imprudent and overuse of clinically relevant antibiotics in agriculture, veterinary and medical
sectors contribute to the global epidemic increase in antimicrobial resistance (AMR). There …

Monitoring antibiotic resistance genes in wastewater treatment: Current strategies and future challenges

AQ Nguyen, HP Vu, LN Nguyen, Q Wang… - Science of the Total …, 2021 - Elsevier
Antimicrobial resistance (AMR) is a growing threat to human and animal health. Progress in
molecular biology has revealed new and significant challenges for AMR mitigation given the …

Long-read metagenomic sequencing reveals shifts in associations of antibiotic resistance genes with mobile genetic elements from sewage to activated sludge

D Dai, C Brown, H Bürgmann, DGJ Larsson, I Nambi… - Microbiome, 2022 - Springer
Background There is concern that the microbially rich activated sludge environment of
wastewater treatment plants (WWTPs) may contribute to the dissemination of antibiotic …

Seizing the moment: now is the time for integrated global surveillance of antimicrobial resistance in wastewater environments

A Pruden, PJ Vikesland, BC Davis… - Current Opinion in …, 2021 - Elsevier
Highlights•Environmental surveillance of AMR is missing from current One Health
strategies.•Integrated surveillance can benefit clinical practice and mitigate the spread of …

Microplastics as hubs enriching antibiotic-resistant bacteria and pathogens in municipal activated sludge

DN Pham, L Clark, M Li - Journal of Hazardous Materials Letters, 2021 - Elsevier
Microplastics can serve as carriers of antibiotic-resistant bacteria (ARB) and pathogens,
representing a pressing concern to aquatic biota and human health. Activated sludge units …

A framework for standardized qPCR-targets and protocols for quantifying antibiotic resistance in surface water, recycled water and wastewater

I Keenum, K Liguori, J Calarco, BC Davis… - Critical Reviews in …, 2022 - Taylor & Francis
Water environments are increasingly recognized as a conduit for the spread of antibiotic
resistance, but there is need to standardize antibiotic resistance monitoring protocols to …

Antibiotic resistomes in drinking water sources across a large geographical scale: Multiple drivers and co-occurrence with opportunistic bacterial pathogens

Z Han, Y Zhang, W An, J Lu, J Hu, M Yang - Water Research, 2020 - Elsevier
Antibiotic resistance genes (ARGs) can survive the water treatment process. However, the
prevalence patterns, key drivers, and relationships with opportunistic pathogens of the …

D-ring modifications of tetracyclines determine their ability to induce resistance genes in the environment

H Tang, Z Liu, B Hu, L Zhu - Environmental Science & Technology, 2023 - ACS Publications
The widespread utilization of tetracyclines (TCs) in agriculture and medicine has led to the
borderless spread of tetracycline resistance in humans, animals, and the environment …

A proposed framework for the identification of indicator genes for monitoring antibiotic resistance in wastewater: Insights from metagenomic sequencing

MH Tarek, E Garner - Science of The Total Environment, 2023 - Elsevier
Antibiotic resistance is one of the greatest threats to global human and animal health of our
time. Municipal wastewater has been identified as a hotspot of antibiotic resistance …