In the pursuit of new pharmaceuticals and agrochemicals, chemists in the life science
industry require access to mild and robust synthetic methodologies to systematically modify …

The development of synthetic methods for the introduction of the fluorine atom and
fluoroalklyl groups into organic molecules has gained increased attention. Synthetic organic …

Fluorinated molecules have a wide range of applications and are used as medicines,
agrochemicals and refrigerants and in smartphone liquid crystal displays, photovoltaic solar …

This review describes the recent advances made in difluoromethylation processes based on
X–CF2H bond formation where X is C (sp), C (sp2), C (sp3), O, N or S, a field of research …

As the “chemical chameleon”, sulfonyl-containing compounds and their variants have been
merged with various types of reactions for the efficient construction of diverse molecular …

Transition metal-catalyzed C–H bond functionalizations have been the focus of intensive
research over the last decades for the formation of C–C bonds from unfunctionalized arenes …

The exceptional versatility of sulfones has been extensively exploited in organic synthesis
across several decades. Since the first demonstration in 2005 that sulfones can participate …

Herein, we report a method for C3-selective C–H tri-and difluoromethylthiolation of
pyridines. The method relies on borane-catalyzed pyridine hydroboration for generation of …

The relevance of the‐CF2H moiety has attracted considerable attention from organic
synthetic and medicinal chemistry communities, because this group can act as a more …

Increasing interest in sustainable chemistry coupled with the quest to explore new reactivity
has spurred research on first-row transition metal complexes for potential applications in a …