Early life microbiota and respiratory tract infections

WAA de Steenhuijsen Piters, J Binkowska, D Bogaert - Cell Host & Microbe, 2020 - cell.com
Over the last decade, it has become clear that respiratory and intestinal tract microbiota are
related to pathogenesis of respiratory tract infections (RTIs). Host and environmental factors …

Virus-Induced Changes of the Respiratory Tract Environment Promote Secondary Infections With Streptococcus pneumoniae

V Sender, K Hentrich… - Frontiers in Cellular and …, 2021 - frontiersin.org
Secondary bacterial infections enhance the disease burden of influenza infections
substantially. Streptococcus pneumoniae (the pneumococcus) plays a major role in the …

Inflammation induced by influenza virus impairs human innate immune control of pneumococcus

SP Jochems, F Marcon, BF Carniel, M Holloway… - Nature …, 2018 - nature.com
Colonization of the upper respiratory tract by pneumococcus is important both as a
determinant of disease and for transmission into the population. The immunological …

Streptococcus pneumoniae colonization associates with impaired adaptive immune responses against SARS-CoV-2

E Mitsi, J Reiné, BC Urban, C Solórzano… - The Journal of clinical …, 2022 - jci.org
Background Although recent epidemiological data suggest that pneumococci may contribute
to the risk of SARS-CoV-2 disease, cases of coinfection with Streptococcus pneumoniae in …

Effect of 13-valent pneumococcal conjugate vaccine on experimental carriage of Streptococcus pneumoniae serotype 6B in Blantyre, Malawi: a randomised controlled …

D Dula, B Morton, T Chikaonda, AE Chirwa… - The Lancet …, 2023 - thelancet.com
Background The effect of childhood pneumococcal conjugate vaccine implementation in
Malawi is threatened by absence of herd effect. There is persistent vaccine-type …

Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine

WAA de Steenhuijsen Piters, SP Jochems… - Nature …, 2019 - nature.com
Streptococcus pneumoniae is the main bacterial pathogen involved in pneumonia.
Pneumococcal acquisition and colonization density is probably affected by viral co …

Inflammation as a modulator of host susceptibility to pulmonary influenza, pneumococcal, and co-infections

ER Aguilera, LL Lenz - Frontiers in immunology, 2020 - frontiersin.org
Bacterial and viral pathogens are predominant causes of pulmonary infections and
complications. Morbidity and mortality from these infections is increased in populations that …

[HTML][HTML] Upper airways colonisation of Streptococcus pneumoniae in adults aged 60 years and older: a systematic review of prevalence and individual participant data …

EL Smith, H Adler, DM Ferreira, R Sá-Leão… - Journal of Infection, 2020 - Elsevier
Summary Background Colonisation with Streptococcus pneumoniae can lead to invasive
pneumococcal disease and pneumonia. Pneumococcal acquisition and prevalence of …

Menstrual hygiene management practices and associated health outcomes among school-going adolescents in rural Gambia

HM Nabwera, V Shah, R Neville, F Sosseh… - PloS one, 2021 - journals.plos.org
Inadequate menstrual hygiene management (MHM) practices have been associated with
adverse health outcomes. This study aimed to describe MHM practices among schoolgirls …

Pneumococcal colonization impairs mucosal immune responses to live attenuated influenza vaccine

BF Carniel, F Marcon, J Rylance, EL German… - JCI …, 2021 - pmc.ncbi.nlm.nih.gov
Influenza virus infections affect millions of people annually, and current available vaccines
provide varying rates of protection. However, the way in which the nasal microbiota …