Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
Tumor biomarkers for diagnosis, prognosis and targeted therapy
Y Zhou, L Tao, J Qiu, J Xu, X Yang, Y Zhang… - Signal transduction and …, 2024 - nature.com
Tumor biomarkers, the substances which are produced by tumors or the body's responses to
tumors during tumorigenesis and progression, have been demonstrated to possess critical …
tumors during tumorigenesis and progression, have been demonstrated to possess critical …
DNA damage response revisited: the p53 family and its regulators provide endless cancer therapy opportunities
Y Abuetabh, HH Wu, C Chai, H Al Yousef… - … & molecular medicine, 2022 - nature.com
Antitumor therapeutic strategies that fundamentally rely on the induction of DNA damage to
eradicate and inhibit the growth of cancer cells are integral approaches to cancer therapy …
eradicate and inhibit the growth of cancer cells are integral approaches to cancer therapy …
DNA damage response signaling pathways and targets for radiotherapy sensitization in cancer
RX Huang, PK Zhou - Signal transduction and targeted therapy, 2020 - nature.com
Radiotherapy is one of the most common countermeasures for treating a wide range of
tumors. However, the radioresistance of cancer cells is still a major limitation for …
tumors. However, the radioresistance of cancer cells is still a major limitation for …
Engineering radiosensitizer‐based metal‐phenolic networks potentiate STING pathway activation for advanced radiotherapy
Radiotherapy, a mainstay of first‐line cancer treatment, suffers from its high‐dose radiation‐
induced systemic toxicity and radioresistance caused by the immunosuppressive tumor …
induced systemic toxicity and radioresistance caused by the immunosuppressive tumor …
Radiotherapy and immunotherapy promote tumoral lipid oxidation and ferroptosis via synergistic repression of SLC7A11
A challenge in oncology is to rationally and effectively integrate immunotherapy with
traditional modalities, including radiotherapy. Here, we demonstrate that radiotherapy …
traditional modalities, including radiotherapy. Here, we demonstrate that radiotherapy …
ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4
Ferroptosis is a newly characterized form of programmed cell death, which is driven by the
lethal accumulation of lipid peroxides catalyzed by the intracellular bioactive iron. Targeted …
lethal accumulation of lipid peroxides catalyzed by the intracellular bioactive iron. Targeted …
Radiotherapy as a tool to elicit clinically actionable signalling pathways in cancer
A variety of targeted anticancer agents have been successfully introduced into clinical
practice, largely reflecting their ability to inhibit specific molecular alterations that are …
practice, largely reflecting their ability to inhibit specific molecular alterations that are …
DNA repair pathways in cancer therapy and resistance
L Li, Y Guan, X Chen, J Yang, Y Cheng - Frontiers in pharmacology, 2021 - frontiersin.org
DNA repair pathways are triggered to maintain genetic stability and integrity when
mammalian cells are exposed to endogenous or exogenous DNA-damaging agents. The …
mammalian cells are exposed to endogenous or exogenous DNA-damaging agents. The …
Strategies for structural modification of small molecules to improve blood–brain barrier penetration: a recent perspective
B **ong, Y Wang, Y Chen, S **ng, Q Liao… - Journal of Medicinal …, 2021 - ACS Publications
In the development of central nervous system (CNS) drugs, the blood–brain barrier (BBB)
restricts many drugs from entering the brain to exert therapeutic effects. Although many …
restricts many drugs from entering the brain to exert therapeutic effects. Although many …
DNA damage checkpoint kinases in cancer
DNA damage response (DDR) pathway prevents high level endogenous and environmental
DNA damage being replicated and passed on to the next generation of cells via an …
DNA damage being replicated and passed on to the next generation of cells via an …