High-throughput methods in the discovery and study of biomaterials and materiobiology
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …
pivotal role in the development of novel implants, biomedical devices, and tissue …
[HTML][HTML] Advances and challenges in stem cell culture
C McKee, GR Chaudhry - Colloids and surfaces B: Biointerfaces, 2017 - Elsevier
Stem cells (SCs) hold great promise for cell therapy, tissue engineering, and regenerative
medicine as well as pharmaceutical and biotechnological applications. They have the …
medicine as well as pharmaceutical and biotechnological applications. They have the …
Spheroid culture of mesenchymal stem cells
Z Cesarz, K Tamama - Stem cells international, 2016 - Wiley Online Library
Compared with traditional 2D adherent cell culture, 3D spheroidal cell aggregates, or
spheroids, are regarded as more physiological, and this technique has been exploited in the …
spheroids, are regarded as more physiological, and this technique has been exploited in the …
Natural biomaterials for cardiac tissue engineering: a highly biocompatible solution
Cardiovascular diseases (CVD) constitute a major fraction of the current major global
diseases and lead to about 30% of the deaths, ie, 17.9 million deaths per year. CVD include …
diseases and lead to about 30% of the deaths, ie, 17.9 million deaths per year. CVD include …
Three-dimensional spheroid culture of human mesenchymal stem cells: offering therapeutic advantages and in vitro glimpses of the in vivo state
BL Yen, CC Hsieh, PJ Hsu, CC Chang… - Stem cells …, 2023 - academic.oup.com
As invaluable as the standard 2-dimensional (2D) monolayer in vitro cell culture system has
been, there is increasing evidence that 3-dimensional (3D) non-adherent conditions are …
been, there is increasing evidence that 3-dimensional (3D) non-adherent conditions are …
Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties
TJ Bartosh, JH Ylöstalo… - Proceedings of the …, 2010 - National Acad Sciences
Previous reports suggested that culture as 3D aggregates or as spheroids can increase the
therapeutic potential of the adult stem/progenitor cells referred to as mesenchymal stem …
therapeutic potential of the adult stem/progenitor cells referred to as mesenchymal stem …
Three-dimensional brain-on-a-chip with an interstitial level of flow and its application as an in vitro model of Alzheimer's disease
There has been a growing need for in vitro models of neurodegenerative diseases such as
Alzheimer's disease that would enable a better understanding of etiology and faster …
Alzheimer's disease that would enable a better understanding of etiology and faster …
Physical cues of biomaterials guide stem cell differentiation fate
Millions of people lose or damage their organs or tissues due to disease, birth defects, or
accidents each year. Stem cells, such as embryonic stem cells (ESCs), induced pluripotent …
accidents each year. Stem cells, such as embryonic stem cells (ESCs), induced pluripotent …
Three-dimensional aggregates of mesenchymal stem cells: cellular mechanisms, biological properties, and applications
Mesenchymal stem cells (MSCs) are primary candidates in cell therapy and tissue
engineering and are being tested in clinical trials for a wide range of diseases. Originally …
engineering and are being tested in clinical trials for a wide range of diseases. Originally …
Increased mesenchymal stem cell functionalization in three-dimensional manufacturing settings for enhanced therapeutic applications
Mesenchymal stem/stromal cell (MSC) exist within their in vivo niches as part of
heterogeneous cell populations, exhibiting variable stemness potential and supportive …
heterogeneous cell populations, exhibiting variable stemness potential and supportive …