Matrix metalloproteinases are involved in cardiovascular diseases

A Azevedo, AF Prado, RC Antonio… - Basic & Clinical …, 2014 - Wiley Online Library
This MiniReview describes the essential biochemical and molecular aspects of matrix
metalloproteinases (MMP s) and briefly discusses how they engage in different diseases …

Relationships between abnormal MMP2 expression and prognosis in gastric cancer: a meta-analysis of cohort studies

HL Wang, PY Zhou, Y Zhang, P Liu - Cancer Biotherapy and …, 2014 - liebertpub.com
We carried out this current meta-analysis of relevant cohort studies in an attempt to
investigate the relationships between abnormal matrix metalloproteinases-2 (MMP2) …

[HTML][HTML] Nebivolol attenuates prooxidant and profibrotic mechanisms involving TGF-β and MMPs, and decreases vascular remodeling in renovascular hypertension

CS Ceron, E Rizzi, DA Guimarães… - Free Radical Biology …, 2013 - Elsevier
Nebivolol and metoprolol are β 1-adrenergic receptor blockers with different properties. We
hypothesized that nebivolol, but not metoprolol, could attenuate prooxidant and profibrotic …

N-Terminomic Identification of Intracellular MMP-2 Substrates in Cardiac Tissue

B Hartley, W Bassiouni, A Roczkowsky… - Journal of Proteome …, 2024 - ACS Publications
Proteases are enzymes that induce irreversible post-translational modifications by
hydrolyzing amide bonds in proteins. One of these proteases is matrix metalloproteinase-2 …

Elevated serum matrix metalloprotease (MMP-2) as a candidate biomarker for stable COPD

D Mahor, V Kumari, K Vashisht, R Galgalekar… - BMC pulmonary …, 2020 - Springer
Background The increasing trend of Chronic Obstructive Pulmonary Disease (COPD) in
becoming the third leading cause of deaths by 2020 is of great concern, globally as well as …

[HTML][HTML] Atorvastatin and sildenafil decrease vascular TGF-β levels and MMP-2 activity and ameliorate arterial remodeling in a model of renovascular hypertension

DA Guimarães, E Rizzi, CS Ceron, A Martins-Oliveira… - Redox biology, 2015 - Elsevier
Abstract Imbalanced matrix metalloproteinase (MMP)-2 activity and transforming growth
factor expression (TGF-β) are involved in vascular remodeling of hypertension. Atorvastatin …