Oxytocin, neural plasticity, and social behavior

RC Froemke, LJ Young - Annual Review of Neuroscience, 2021 - annualreviews.org
Oxytocin regulates parturition, lactation, parental nurturing, and many other social behaviors
in both sexes. The circuit mechanisms by which oxytocin modulates social behavior are …

The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Therapeutic potential of vasopressin in the treatment of neurological disorders

S Mishra, J Grewal, P Wal, GU Bhivshet, AK Tripathi… - Peptides, 2024 - Elsevier
Vasopressin (VP) is a nonapeptide made of nine amino acids synthesized by the
hypothalamus and released by the pituitary gland. VP acts as a neurohormone …

What is resilience: an affiliative neuroscience approach

R Feldman - World psychiatry, 2020 - Wiley Online Library
Resilience–a key topic in clinical science and practice–still lacks a clear conceptualization
that integrates its evolutionary and human‐specific features, refrains from exclusive focus on …

The central nucleus of the amygdala and the construction of defensive modes across the threat-imminence continuum

JM Moscarello, MA Penzo - Nature Neuroscience, 2022 - nature.com
In nature, animals display defensive behaviors that reflect the spatiotemporal distance of
threats. Laboratory-based paradigms that elicit specific defensive responses in rodents have …

Neuronal circuits for fear and anxiety

P Tovote, JP Fadok, A Lüthi - Nature Reviews Neuroscience, 2015 - nature.com
Decades of research has identified the brain areas that are involved in fear, fear extinction,
anxiety and related defensive behaviours. Newly developed genetic and viral tools …

Oxytocin enables maternal behaviour by balancing cortical inhibition

BJ Marlin, M Mitre, JA D'amour, MV Chao, RC Froemke - Nature, 2015 - nature.com
Oxytocin is important for social interactions and maternal behaviour. However, little is known
about when, where and how oxytocin modulates neural circuits to improve social cognition …

Vasopressin and oxytocin receptor systems in the brain: sex differences and sex-specific regulation of social behavior

KM Dumais, AH Veenema - Frontiers in neuroendocrinology, 2016 - Elsevier
The neuropeptides vasopressin (VP) and oxytocin (OT) and their receptors in the brain are
involved in the regulation of various social behaviors and have emerged as drug targets for …

[HTML][HTML] Oxytocin in general anxiety and social fear: a translational approach

ID Neumann, DA Slattery - Biological psychiatry, 2016 - Elsevier
The neuropeptide oxytocin (OXT) has been revealed as a profound anxiolytic and antistress
factor of the brain, besides its many prosocial and reproductive effects. Therefore, there is …

New perspectives on central amygdala function

JP Fadok, M Markovic, P Tovote, A Lüthi - Current opinion in neurobiology, 2018 - Elsevier
Highlights•Central amygdala circuits mediate defensive and appetitive responses.•Central
amygdala circuit activity is controlled by local inhibitory interactions.•Central amygdala …