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American Association of Clinical Endocrinology clinical practice guideline for the diagnosis and management of nonalcoholic fatty liver disease in primary care and …
K Cusi, S Isaacs, D Barb, R Basu, S Caprio… - Endocrine Practice, 2022 - Elsevier
Objective To provide evidence-based recommendations regarding the diagnosis and
management of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis …
management of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis …
Defining paediatric metabolic (dysfunction)-associated fatty liver disease: an international expert consensus statement
The term non-alcoholic fatty liver disease (NAFLD), and its definition, have limitations for
both adults and children. The definition is most problematic for children, for whom alcohol …
both adults and children. The definition is most problematic for children, for whom alcohol …
Clinical practice guideline for the evaluation and treatment of children and adolescents with obesity
You have in your hands, or at your fingertips, the first edition of the American Academy of
Pediatrics clinical practice guideline for evaluation and management of children and …
Pediatrics clinical practice guideline for evaluation and management of children and …
Obesity I: Overview and molecular and biochemical mechanisms
Obesity is a chronic, relapsing condition characterized by excess body fat. Its prevalence
has increased globally since the 1970s, and the number of obese and overweight people is …
has increased globally since the 1970s, and the number of obese and overweight people is …
Glucocorticoids, their uses, sexual dimorphisms, and diseases: new concepts, mechanisms, and discoveries
The normal stress response in humans is governed by the hypothalamic-pituitary-adrenal
(HPA) axis through heightened mechanisms during stress, raising blood levels of the …
(HPA) axis through heightened mechanisms during stress, raising blood levels of the …
Pediatric obesity: complications and current day management
Obesity affects approximately 1 in 5 youth globally and increases the risk of complications
during adolescence and young adulthood, including type 2 diabetes, dyslipidemia …
during adolescence and young adulthood, including type 2 diabetes, dyslipidemia …
[HTML][HTML] A natural history study of paediatric non-alcoholic fatty liver disease over 10 years
L Draijer, M Voorhoeve, M Troelstra, A Holleboom… - JHEP Reports, 2023 - Elsevier
Background & Aims The long-term outcome of paediatric non-alcoholic fatty liver disease
(NAFLD) has not been well established. Between 2008 and 2012, an unselected cohort of …
(NAFLD) has not been well established. Between 2008 and 2012, an unselected cohort of …
Intensive lifestyle management improves steatosis and fibrosis in pediatric nonalcoholic fatty liver disease
Background & Aims Childhood obesity, with associated comorbidities such as nonalcoholic
fatty liver disease (NAFLD), is an increasing global health problem. Although lifestyle …
fatty liver disease (NAFLD), is an increasing global health problem. Although lifestyle …
Suppressing hepatic UGT1A1 increases plasma bilirubin, lowers plasma urobilin, reorganizes kinase signaling pathways and lipid species and improves fatty liver …
Several population studies have observed lower serum bilirubin levels in patients with non-
alcoholic fatty liver disease (NAFLD). Yet, treatments to target this metabolic phenotype have …
alcoholic fatty liver disease (NAFLD). Yet, treatments to target this metabolic phenotype have …
Zonation in NASH–A key paradigm for understanding pathophysiology and clinical outcomes
Non‐alcoholic fatty liver disease (NAFLD) exists as a spectrum ranging from simple
steatosis to histologically defined hepatocyte injury and inflammatory changes that define …
steatosis to histologically defined hepatocyte injury and inflammatory changes that define …