[HTML][HTML] Metabolic syndrome: updates on pathophysiology and management in 2021

G Fahed, L Aoun, M Bou Zerdan, S Allam… - International journal of …, 2022 - mdpi.com
Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …

A new immunometabolic perspective of intervertebral disc degeneration

V Francisco, J Pino, MÁ González-Gay… - Nature Reviews …, 2022 - nature.com
Intervertebral disc (IVD) degeneration is a common finding on spine imaging that increases
in prevalence with age. IVD degeneration is a frequent cause of low back pain, which is a …

Obesity phenotypes and cardiovascular risk: From pathophysiology to clinical management

A Preda, F Carbone, A Tirandi, F Montecucco… - Reviews in Endocrine …, 2023 - Springer
Obesity epidemic reached the dimensions of a real global health crisis with more than one
billion people worldwide living with obesity. Multiple obesity-related mechanisms cause …

Bone marrow mesenchymal stromal cells: identification, classification, and differentiation

Q Gao, L Wang, S Wang, B Huang, Y **g… - Frontiers in cell and …, 2022 - frontiersin.org
Bone marrow mesenchymal stromal cells (BMSCs), identified as pericytes comprising the
hematopoietic niche, are a group of heterogeneous cells composed of multipotent stem …

Progress in understanding metabolic syndrome and knowledge of its complex pathophysiology

BK Jha, ML Sherpa, M Imran, Y Mohammed, LA Jha… - Diabetology, 2023 - mdpi.com
The metabolic syndrome (MetS), first introduced by Haller in 1975, was sometimes also
known as insulin resistance syndrome, syndrome X, and plurimetabolic syndrome. In 1989 …

[HTML][HTML] Use of physical activity and exercise to reduce inflammation in children and adolescents with obesity

V Calcaterra, M Vandoni, V Rossi, C Berardo… - International journal of …, 2022 - mdpi.com
Childhood obesity is a leading public health problem worldwide, as it is increasingly
prevalent and therefore responsible for serious obesity-related comorbidities, not only in …

[HTML][HTML] The interplay between obesity and inflammation

I Savulescu-Fiedler, R Mihalcea, S Dragosloveanu… - Life, 2024 - mdpi.com
Obesity is an important condition affecting the quality of life of numerous patients and
increasing their associated risk for multiple diseases, including tumors and immune …

[HTML][HTML] Adipokines in non-alcoholic fatty liver disease: are we on the road toward new biomarkers and therapeutic targets?

V Francisco, MJ Sanz, JT Real, P Marques… - Biology, 2022 - mdpi.com
Simple Summary Non-alcoholic fatty liver disease (NAFLD) is an unmet medical need due to
its increasingly high incidence, severe clinical consequences, and the absence of feasible …

Spaceflight induces changes in gene expression profiles linked to insulin and estrogen

BA Mathyk, M Tabetah, R Karim, V Zaksas… - Communications …, 2024 - nature.com
Organismal adaptations to spaceflight have been characterized at the molecular level in
model organisms, including Drosophila and C. elegans. Here, we extend molecular work to …

Obesity-dependent adipokine chemerin suppresses fatty acid oxidation to confer ferroptosis resistance

SK Tan, I Mahmud, F Fontanesi, M Puchowicz… - Cancer …, 2021 - aacrjournals.org
Clear cell renal cell carcinoma (ccRCC) is characterized by accumulation of neutral lipids
and adipogenic transdifferentiation. We assessed adipokine expression in ccRCC and …