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[HTML][HTML] Metabolic syndrome: updates on pathophysiology and management in 2021
Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …
A new immunometabolic perspective of intervertebral disc degeneration
V Francisco, J Pino, MÁ González-Gay… - Nature Reviews …, 2022 - nature.com
Intervertebral disc (IVD) degeneration is a common finding on spine imaging that increases
in prevalence with age. IVD degeneration is a frequent cause of low back pain, which is a …
in prevalence with age. IVD degeneration is a frequent cause of low back pain, which is a …
Obesity phenotypes and cardiovascular risk: From pathophysiology to clinical management
Obesity epidemic reached the dimensions of a real global health crisis with more than one
billion people worldwide living with obesity. Multiple obesity-related mechanisms cause …
billion people worldwide living with obesity. Multiple obesity-related mechanisms cause …
Bone marrow mesenchymal stromal cells: identification, classification, and differentiation
Q Gao, L Wang, S Wang, B Huang, Y **g… - Frontiers in cell and …, 2022 - frontiersin.org
Bone marrow mesenchymal stromal cells (BMSCs), identified as pericytes comprising the
hematopoietic niche, are a group of heterogeneous cells composed of multipotent stem …
hematopoietic niche, are a group of heterogeneous cells composed of multipotent stem …
Progress in understanding metabolic syndrome and knowledge of its complex pathophysiology
The metabolic syndrome (MetS), first introduced by Haller in 1975, was sometimes also
known as insulin resistance syndrome, syndrome X, and plurimetabolic syndrome. In 1989 …
known as insulin resistance syndrome, syndrome X, and plurimetabolic syndrome. In 1989 …
[HTML][HTML] Use of physical activity and exercise to reduce inflammation in children and adolescents with obesity
Childhood obesity is a leading public health problem worldwide, as it is increasingly
prevalent and therefore responsible for serious obesity-related comorbidities, not only in …
prevalent and therefore responsible for serious obesity-related comorbidities, not only in …
[HTML][HTML] The interplay between obesity and inflammation
I Savulescu-Fiedler, R Mihalcea, S Dragosloveanu… - Life, 2024 - mdpi.com
Obesity is an important condition affecting the quality of life of numerous patients and
increasing their associated risk for multiple diseases, including tumors and immune …
increasing their associated risk for multiple diseases, including tumors and immune …
[HTML][HTML] Adipokines in non-alcoholic fatty liver disease: are we on the road toward new biomarkers and therapeutic targets?
V Francisco, MJ Sanz, JT Real, P Marques… - Biology, 2022 - mdpi.com
Simple Summary Non-alcoholic fatty liver disease (NAFLD) is an unmet medical need due to
its increasingly high incidence, severe clinical consequences, and the absence of feasible …
its increasingly high incidence, severe clinical consequences, and the absence of feasible …
Spaceflight induces changes in gene expression profiles linked to insulin and estrogen
Organismal adaptations to spaceflight have been characterized at the molecular level in
model organisms, including Drosophila and C. elegans. Here, we extend molecular work to …
model organisms, including Drosophila and C. elegans. Here, we extend molecular work to …
Obesity-dependent adipokine chemerin suppresses fatty acid oxidation to confer ferroptosis resistance
Clear cell renal cell carcinoma (ccRCC) is characterized by accumulation of neutral lipids
and adipogenic transdifferentiation. We assessed adipokine expression in ccRCC and …
and adipogenic transdifferentiation. We assessed adipokine expression in ccRCC and …