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Global trends in hepatocellular carcinoma epidemiology: implications for screening, prevention and therapy
Hepatocellular carcinoma (HCC) mortality rates are increasing globally, and particularly in
the Western world. Cirrhosis remains the predominant risk factor for HCC. However …
the Western world. Cirrhosis remains the predominant risk factor for HCC. However …
Cardiovascular-kidney-metabolic health: a presidential advisory from the American Heart Association
Cardiovascular-kidney-metabolic health reflects the interplay among metabolic risk factors,
chronic kidney disease, and the cardiovascular system and has profound impacts on …
chronic kidney disease, and the cardiovascular system and has profound impacts on …
A phase 3, randomized, controlled trial of resmetirom in NASH with liver fibrosis
SA Harrison, P Bedossa, CD Guy… - … England Journal of …, 2024 - Mass Medical Soc
Background Nonalcoholic steatohepatitis (NASH) is a progressive liver disease with no
approved treatment. Resmetirom is an oral, liver-directed, thyroid hormone receptor beta …
approved treatment. Resmetirom is an oral, liver-directed, thyroid hormone receptor beta …
Tirzepatide for metabolic dysfunction–associated steatohepatitis with liver fibrosis
Background Metabolic dysfunction–associated steatohepatitis (MASH) is a progressive liver
disease associated with liver-related complications and death. The efficacy and safety of …
disease associated with liver-related complications and death. The efficacy and safety of …
A phase 2 randomized trial of survodutide in MASH and fibrosis
AJ Sanyal, P Bedossa, M Fraessdorf… - … England Journal of …, 2024 - Mass Medical Soc
Background Dual agonism of glucagon receptor and glucagon-like peptide-1 (GLP-1)
receptor may be more effective than GLP-1 receptor agonism alone for treating metabolic …
receptor may be more effective than GLP-1 receptor agonism alone for treating metabolic …
Metabolic dysfunction-associated steatotic liver disease (MASLD): a state-of-the-art review
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the latest term for
steatotic liver disease associated with metabolic syndrome. MASLD is the most common …
steatotic liver disease associated with metabolic syndrome. MASLD is the most common …
MASLD: a systemic metabolic disorder with cardiovascular and malignant complications
Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic
liver disease globally and is currently estimated to affect up to 38% of the global adult …
liver disease globally and is currently estimated to affect up to 38% of the global adult …
HIV infection
The AIDS epidemic has been a global public health issue for more than 40 years and has
resulted in~ 40 million deaths. AIDS is caused by the retrovirus, HIV-1, which is transmitted …
resulted in~ 40 million deaths. AIDS is caused by the retrovirus, HIV-1, which is transmitted …
Current status and future trends of the global burden of MASLD
L Miao, G Targher, CD Byrne, YY Cao… - Trends in Endocrinology & …, 2024 - cell.com
Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most
common chronic liver disease globally, affecting more than a third of the world's adult …
common chronic liver disease globally, affecting more than a third of the world's adult …
A synopsis of the evidence for the science and clinical management of cardiovascular-kidney-metabolic (CKM) syndrome: a scientific statement from the American …
CE Ndumele, IJ Neeland, KR Tuttle, SL Chow… - Circulation, 2023 - ahajournals.org
A growing appreciation of the pathophysiological interrelatedness of metabolic risk factors
such as obesity and diabetes, chronic kidney disease, and cardiovascular disease has led …
such as obesity and diabetes, chronic kidney disease, and cardiovascular disease has led …