Natural Products (NP) are essential for the discovery of novel drugs and products for
numerous biotechnological applications. The NP discovery process is expensive and time …

Determining the structure and phenotypic context of molecules detected in untargeted
metabolomics experiments remains challenging. Here we present reverse metabolomics as …

This review examines a wide range of marine microbial-derived bioactive peptide
molecules, emphasizing the significance of reverse engineering in their production. The …

Molecular networking connects mass spectra of molecules based on the similarity of their
fragmentation patterns. However, during ionization, molecules commonly form multiple ion …

Liquid chromatography–mass spectrometry (LC-MS)-based untargeted metabolomics
studies require high-quality spectral libraries for reliable metabolite identification. We have …

Untargeted metabolomics approaches deal with complex data hindering structural
information for the comprehensive analysis of unknown metabolite features. We investigated …

The identification of bioactive natural products (NPs) in complex mixtures has become an
important subject of contemporary NP research. In an attempt to address this challenge, the …

MOLECULAR NETWORKS: AN ANALYSIS ON ANNOTATIONS AND DISCOVERY OF NEW
ASSETS. To speed up the discovery of bioactive natural products (NP), chemists have …

Identification of metabolites in humans remains challenging. Here, we present synthesis-
based reverse metabolomics as a strategy for structure elucidation that aims to also find …

Molecular networking connects tandem mass spectra of molecules based on the similarity of
their fragmentation patterns. However, during ionization, molecules commonly form multiple …