EMC chaperone–CaV structure reveals an ion channel assembly intermediate

Z Chen, A Mondal, F Abderemane-Ali, S Jang… - Nature, 2023 - nature.com
Voltage-gated ion channels (VGICs) comprise multiple structural units, the assembly of
which is required for function,. Structural understanding of how VGIC subunits assemble and …

Vitamin D, calbindin, and calcium signaling: unraveling the Alzheimer's connection

M Acharya, N Singh, G Gupta, MM Tambuwala… - Cellular signalling, 2024 - Elsevier
Calcium is a ubiquitous second messenger that is indispensable in regulating
neurotransmission and memory formation. A precise intracellular calcium level is achieved …

Predicting Mutational Effects on Ca2+-Activated Chloride Conduction of TMEM16A Based on a Simulation Study

Y Zhang, K Wu, Y Li, S Wu, A Warshel… - Journal of the American …, 2024 - ACS Publications
The dysfunction and defects of ion channels are associated with many human diseases,
especially for loss-of-function mutations in ion channels such as cystic fibrosis …

Advances in CaV1.1 gating: New insights into permeation and voltage-sensing mechanisms

H Bibollet, A Kramer, RA Bannister… - Channels, 2023 - Taylor & Francis
ABSTRACT The CaV1. 1 voltage-gated Ca2+ channel carries L-type Ca2+ current and is the
voltage-sensor for excitation-contraction (EC) coupling in skeletal muscle. Significant …

EMC holdase:CaV1.2/CaVβ3 complex and CaV1.2 channel structures reveal CaV assembly and drug binding mechanisms

Z Chen, A Mondal, F Abderemane-Ali, J Montano… - bioRxiv, 2022 - biorxiv.org
Voltage-gated ion channels (VGICs) comprise multiple structural units whose assembly is
required for function,. There is scant structural understanding of how VGIC subunits …

Application of Synthetic Antibodies to Biology: The Engineering of Antibody-Based Tools and Therapeutics

T Slezak - 2023 - search.proquest.com
Antibodies have the unique property of recognizing and binding specific antigens, making
them valuable tools for studying biological processes and develo** new disease …

[CITATION][C] Ion Channels and Transporters-Marco Lolicato

PI Marco Lolicato, C Arrigoni, PIA Bontà, SC Nibali - medicinamolecolare.dip.unipv.it
The goal of the laboratory is the identification (1) of the role of the Hv1 channel in breast
cancer metastases;(2) of the molecular mechanisms of the interactome of the KCC2 …

[CITATION][C] Canali ionici e trasportatori-Marco Lolicato

PI Marco Lolicato, AC Arrigoni, PIA Bontà, SC Nibali - medicinamolecolare.dip.unipv.it
Canali ionici e trasportatori - Marco Lolicato | Dipartimento di Medicina Molecolare Salta al
contenuto principale ml iten icona lente di ricerca icona lente di ricerca Cerca Cerca …