Modern genetics research has resulted in significant advances in cell in vitro microinjection
systems. Such systems provide biological and medical practitioners with high volume cell …

With five decades of sustained application, micropipette aspiration has enabled a wide
range of biomechanical studies in the field of cell mechanics. Here, we provide an update on …

The behaviour of mammalian cells in a tissue is governed by the three-dimensional (3D)
microenvironment and involves a dynamic interplay between biochemical and mechanical …

The causes of embryonic arrest during pre-implantation development are poorly understood.
Attempts to correlate patterns of oocyte gene expression with successful embryo …

In development and differentiation, morphological changes often accompany mechanical
changes [1], but it is unclear whether or when cells in embryos sense tissue elasticity. The …

Robotic manipulation of deformable objects has been a classic topic in robotics. Compared
to synthetic deformable objects such as rubber balls and clothes, biological cells are highly …

Mammalian embryos are surrounded by an acellular shell, the zona pellucida. Hatching out
of the zona is crucial for implantation and continued development of the embryo. Clinically …

During pre‐implantation development, the mammalian zygote transforms into the blastocyst,
the structure that will implant the embryo in the maternal uterus. Consisting of a squamous …

Elasticity is a fundamental cellular property that is related to the anatomy, functionality, and
pathological state of cells and tissues. However, current techniques based on cell …

The overall physical properties of tissues emerge in a complex manner from the properties
of the component cells and other constituent materials from which the tissue is formed …