Poly (lactic-co-glycolic acid)(PLGA) is one of the most successfully developed
biodegradable polymers. Among the different polymers developed to formulate polymeric …

Background Poly (lactic acid)(PLA) and poly (lactic-co-glycolic acid)(PLGA) are among the
well-documented FDA-approved polymers used for the preparation of safe and effective …

Vaccination is the most efficient way to protect humans against pathogens. Peptide-based
vaccines offer several advantages over classical vaccines, which utilized whole organisms …

The concept of therapeutic cancer vaccines is based on the activation of the immune system
against tumor cells after the presentation of tumor antigens. Nanoparticles (NPs) have …

Immunotherapy, as a powerful strategy for cancer treatment, has achieved tremendous
efficacy in clinical trials. Despite these advancements, there is much to do in terms of …

Acquired by inhalation of the thermal dimorphic fungi Paracoccidioides spp. conidia,
paracoccidioidomycosis ranges from symptomatic to severe and potentially fatal …

Dendritic cells play a central role in antigen presentation and generation of cytotoxic T
lymphocyte (CTL) response required for anticancer vaccination. The review focuses on use …

We hypothesized that the co-entrapment of melanoma-associated antigens and the Toll-like
receptor (TLR) ligands Poly (I: C) and CpG, known to be Th1-immunopotentiators, in …

Vaccine adjuvants are applied to amplify the recipient's specific immune responses against
pathogen infection or malignancy. A new generation of adjuvants is being developed to …

Cancer immunotherapy, which harnesses the immune system to fight cancer, has begun to
make a breakthrough in clinical applications. Dendritic cells (DCs) are the bridge linking …