Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

▪ Abstract This article, which is partly biographical and partly scientific, summarizes a life in
academic medicine. It relates my progress from benchside to bedside and then to academic …

Introduction: Hypoxic ischemic encephalopathy (HIE) is the most important reason for
morbidity and mortality in term-born infants. Understanding pathophysiology of the brain …

Perinatal hypoxia-ischemia remains the primary cause of acute neonatal brain injury,
leading to a high mortality rate and long-term neurological deficits, such as behavioral …

This review focuses on the role of prenatal hypoxia in the development of brain functions in
the postnatal period and subsequent increased risk of neurodegenerative disorders in later …

Neonatal hypoxic ischemic encephalopathy (HIE) is a devastating disease that primarily
causes neuronal and white matter injury and is among the leading cause of death among …

There is currently no approved neuroprotective pharmacotherapy for acute conditions such
as stroke and cerebral asphyxia. One of the reasons for this may be the multiplicity of cell …

Cerebral palsy (CP) is a complex multifactorial disorder, affecting approximately 2.5–3/1000
live term births, and up to 22/1000 prematurely born babies. CP results from injury to the …

Preconditioning is a phenomenon in which brief episodes of a sublethal insult induce robust
protection against subsequent lethal injuries. Preconditioning has been observed in multiple …

Asrocytic responses constitute one of the earliest and most prominent changes in the CNS
following ischemic injury. Astrocytes are known to carry out critical functions such as …