To date, a large number of long non-coding RNAs (lncRNAs) have been recently discovered
through functional genomics studies. Importantly, lncRNAs have been shown, in many …

A significant portion of the human genome encodes genes that transcribe long nonprotein-
coding RNAs (lncRNAs). A large number of lncRNAs localize in the nucleus, either enriched …

HuR influences gene expression programs and hence cellular phenotypes by binding to
hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular …

Accumulating evidence indicates that long non-coding RNAs (lncRNAs) can play a pivotal
role in regulation of diverse cellular processes. In particular, lncRNAs can serve as master …

In recent years, long noncoding RNAs (lncRNAs) have emerged as an important class of
regulators of gene expression. lncRNAs exhibit several distinctive features that confer …

Understanding the mechanisms of androgen receptor (AR) activation in the milieu of low
androgen is critical to effective treatment of castration-resistant prostate cancer (CRPC) …

Hepatocellular cancers (HCC) are highly resistant to chemotherapy. TGFβ has been
associated with chemoresistance in some human cancers but the mechanisms involved are …

Metastasis is the primary cause of cancer-related death all over the world. Metastasis is a
process by which cancer spreads from the place at which it first arose to distant locations in …

Breast cancer is a malignant tumor that has a high mortality rate and mostly occurs in
women. Although significant progress has been made in the implementation of personalized …

In addition to protein-coding genes, the human genome makes a large amount of noncoding
RNAs, including microRNAs and long noncoding RNAs (lncRNAs). Both microRNAs and …