The human obesity gene map: the 2005 update

T Rankinen, A Zuberi, YC Chagnon, SJ Weisnagel… - …, 2006 - Wiley Online Library
This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

Genetics of body-weight regulation

GS Barsh, IS Farooqi, S O'rahilly - Nature, 2000 - nature.com
The role of genetics in obesity is twofold. Studying rare mutations in humans and model
organisms provides fundamental insight into a complex physiological process, and …

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

C Fleury, M Neverova, S Collins, S Raimbault… - Nature …, 1997 - nature.com
A mitochondrial protein called uncoupling protein (UCP1) plays an important role in
generating heat and burning calories by creating a pathway that allows dissipation of the …

The human obesity gene map: the 2003 update

EE Snyder, B Walts, L Pérusse, YC Chagnon… - Obesity …, 2004 - Wiley Online Library
This is the tenth update of the human obesity gene map, incorporating published results up
to the end of October 2003 and continuing the previous format. Evidence from single‐gene …

The human obesity gene map: the 2004 update

L Pérusse, T Rankinen, A Zuberi, YC Chagnon… - Obesity …, 2005 - Wiley Online Library
This paper presents the eleventh update of the human obesity gene map, which
incorporates published results up to the end of October 2004. Evidence from single‐gene …

Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing

LD Fricker, AA McKinzie, J Sun, E Curran… - Journal of …, 2000 - jneurosci.org
Five novel peptides were identified in the brains of mice lacking active carboxypeptidase E,
a neuropeptide-processing enzyme. These peptides are produced from a single precursor …

The human obesity gene map: the 2002 update

YC Chagnon, T Rankinen, EE Snyder… - Obesity …, 2003 - Wiley Online Library
This is the ninth update of the human obesity gene map, incorporating published results
through October 2002 and continuing the previous format. Evidence from single‐gene …

Developmental quantitative genetics, conditional epigenetic variability and growth in mice

WR Atchley, J Zhu - Genetics, 1997 - academic.oup.com
Ontogenetic variation in the causal components of phenotypic variability and covariability is
described for body weight and tail length in mice derived from a full 7× 7 diallel cross. Age …

The human obesity gene map: the 2001 update

T Rankinen, L Pérusse, SJ Weisnagel… - Obesity …, 2002 - Wiley Online Library
This report constitutes the eighth update of the human obesity gene map, incorporating
published results up to the end of October 2001. Evidence from the rodent and human …

Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map

F Lammert, MC Carey, B Paigen - Gastroenterology, 2001 - Elsevier
Epidemiologic and family studies indicate that cholesterol gallstone formation is in part
genetically determined. The major contribution to our current understanding of gallstone …